13 documents found, page 1 of 2

Ketamine combined with psychotherapy for treatment-resistant depression

Ketamine, an N -methyl- d -aspartate antagonist, shows promise for treatment-resistant depression (TRD), with psychedelic doses potentially enhancing efficacy. However, its transient antidepressant effects and the need for repeated infusions raise concerns about optimal duration and long-term safety. Two clinical trials have tested the combination of ketamine with psychotherapy for depression, with mixed result...

Transforming Healthcare: Prioritizing Psychological Trauma through Trauma-Infor...

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Community Psychiatry in a Favela in Brazil: Portrait of a Psychosocial Care Cen...

A Patient With Mental Disorder Wrongly Detained in a European Migrant Detention...

The admission of undocumented migrants and refugees to detention centres (DC) has been systematically associated with several poor mental health outcomes. Much less is known about people with mental health disorders, non-migrants, who might be wrongfully committed to these facilities. This article draws on Dave's case, where a German citizen was detained in a migrant DC in Porto. The patient was later treated a...

Drug Delivery Systems and Flavonoids: Current Knowledge in Melanoma Treatment a...

Melanoma is an aggressive form of skin cancer with a high prevalence in the population. An early diagnosis is crucial to cure this disease. Still, when this is not possible, combining potent pharmacological agents and effective drug delivery systems is essential to achieve optimal treatment and improve patients' quality of life. Nanotechnology application in biomedical sciences to encapsulate anticancer drugs, ...

Cantinho do Tareco - uma app para a adoção de animais

O presente projeto centra-se no desenvolvimento de uma aplicação móvel a partir de uma investigação sobre User Interface e User Experience. Pretende-se com esta aplicação simplificar os processos atuais da Associação de Proteção Animal Cantinho do Tareco e transformá-los em processos mais eficientes e intuitivos. A principal funcionalidade da aplicação distingue-se pela sua base no processo de adoção, ainda que...

Role of a micronized purified flavonoid fraction as an adjuvant treatment to ru...

Nonsurgical treatment of hemorrhoidal disease (HD) includes medical and instrumental techniques. We aimed to compare the efficacy of the most frequently used nonsurgical strategies, either alone or in combination, applied in an ambulatory setting. Purpose: Nonsurgical treatment of hemorrhoidal disease (HD) includes medical and instrumental techniques. We aimed to compare the efficacy of the most frequently used...

No rasto da devoção: escultura em pedra no Convento de Cristo: séculos XIV a XVI

"No rasto da devoção: escultura em pedra no Convento de Cristo: séculos XIV a XVI" - Catálogo da Exposição. Na expectativa da recuperação de uma parte, ainda que ínfima, do universo devocional que motivou a criação das esculturas patentes nesta exposição, e que durante vários séculos lhes deu sentido e contexto, construiu-se uma narrativa iconológica que parte das figuras e temas que protagonizam o núcleo escul...

Os efeitos das técnicas de ultra-som e mobilização na capsulite adesiva: uma re...

Objectivo: Compreender os efeitos das técnicas de ultra-som e da mobilização na capsulite adesiva. Metodologia: Pesquisa computorizada nas bases de dados B-on, Pubmed, EBSCO, PEDro e Science Direct para identificar estudos que avaliaram os efeitos das técnicas de ultra-som e da mobilização na capsulite adesiva. Resultados: Nesta revisão foram incluídos 5 artigos envolvendo 183 indivíduos, com classificação meto...

MicroRNA deregulation and chemotaxis and phagocytosis impairment in Alzheimer's...

Introduction: Mononuclear phagocytes play a critical role during Alzheimer’s disease (AD) pathogenesis due to their contribution to innate immune responses and amyloid beta (Ab) clearance mechanisms. Methods: Blood-derived monocytes (BDMs) and monocyte-derived macrophages (MDMs) were isolated from blood of AD, mild cognitive impairment (MCI) patients, and age-matched healthy controls for molecular and phenotypi...