7 documents found, page 1 of 1
Estudo farmacológico e fisiopatológico em camundongos infectados com Plasmodium...
Cunha, Fernando QueirozMice experimentally infected with PZa^two c(Zu.m betg/ieZ , demonstrated the following physiopathological alterations during seven days of malarial infection: reduction in haematocrit, in- creases in parasitized erythrocytes, pulmonary edema,hipothermi_ a, formation of prostaglandin-like substances in the central nervous system, increases of plasma bradykininogen leveis up to the 6th day of infection, and decre...
TLR4 deficiency upregulates TLR9 expression and enhances irinotecan-related int...
Wong, Deysi Viviana Tenazoa; Holanda, Renata Brito Falcão; Cajado, Aurilene Gomes; Bandeira, Alessandro Maia; Pereira, Jorge Fernando BessaMade available in DSpace on 2022-05-01T07:58:47Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-10-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico; Background and purpose: Severe diarrhoea, a common gastrointestinal manifestation of anticanc...
Taurine supplementation increases irisin levels after high intensity physical t...
Batitucci, Gabriela [UNESP]; Cunha Brandao, Camila Fernanda; De Carvalho, Flavia Giolo; Marchini, Julio Sergio; Pfrimer, Karma; Ferrioli, EduardoMade available in DSpace on 2020-12-10T19:36:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-11-01; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Background: Irisin is a myokine/adipokine that under stimulus of physical exercise is able to improve thermogenic capacity in adipose tissue. Likewise, taurine supplementat...
Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation...
Lemos, Henrique Paula; Grespan, Renata; Manfredo Vieira, Silvio; Cunha, Thiago Mattar; Verri, Waldiceu A.; Fernandes, Karla S.; Souto, Fabrício OliveiraIL-23/IL-17-induced neutrophil recruitment plays a pivotal role in rheumatoid arthritis (RA). However, the mechanism of the neutrophil recruitment is obscure. Here we report that prostaglandin enhances the IL-23/IL-17-induced neutrophil migration in a murine model of RA by inhibiting IL-12 and IFN γ production. Methylated BSA (mBSA) and IL-23-induced neutrophil migration was inhibited by anti-IL-23 and anti-IL-...
Joint NOD2/RIPK2 signaling regulates IL-17 axis and contributes to the developm...
Manfredo Vieira, Silvio; Cunha, Thiago Mattar; França, Rafael Freitas de Oliveira; Pinto, Larissa Garcia; Talbot, Jhimmy; Turato, Walter MiguelIntracellular pattern recognition receptors such as the nucleotide-binding oligomerization domain (NOD)-like receptors family members are key for innate immune recognition of microbial infection and may play important roles in the development of inflammatory diseases, including rheumatic diseases. In this study, we evaluated the role of NOD1 and NOD2 on development of experimental arthritis. Ag-induced arthriti...
The pattern of immune cell infiltration in chromoblastomycosis: involvement of ...
Sá, Vanuza Cristina; Silva, Tarcília Aparecida; Reis, Carmelia Matos Santiago; Cunha, Fernando Queiroz; Figueiredo, FlorêncioMade available in DSpace on 2016-10-10T03:51:20Z (GMT). No. of bitstreams: 2 The pattern of immune cell.pdf: 241268 bytes, checksum: 1e0c03fd87d06624c454cb48b807a815 (MD5) license.txt: 1818 bytes, checksum: 46de3043f08e87659ae535ef74b8ce9d (MD5) Previous issue date: 2007-01; A cromomicose é micose subcutânea crônica sistêmica caracterizada por resposta inflamatória crônica granulomatosa. No entanto, existem pou...
Padrão de infiltração de células do sistema imune na cromomicose: envolvimento ...
Sá, Vanuza Cristina; Silva, Tarcília Aparecida; Reis, Carmelia Matos Santiago; Cunha, Fernando Queiroz; Figueiredo, FlorêncioChromoblastomycosis (CR) is a subcutaneous chronic mycosis characterized by a granulomatous inflammatory response. However, little is known regarding the pattern of leukocyte subsets in CR and the pathways involved in their recruitment. The objective of this study was to assess the cellular subsets, chemokine, chemokine receptors and enzymes in CR. The inflammatory infiltrate was characterized by immunohistoche...