28 documents found, page 1 of 3

Characterization of individual mobility for non-routine scenarios from Crowd Se...

Demand for leisure activities has increased due to some reasons such as increasing wealth, ageing populations and changing lifestyles, however, the efficiency of public transport system relies on solid demand levels and well-established mobility patterns and, so, providing quality public transportation is extremely expensive in low, variable and unpredictable demand scenarios, as it is the case of out-of-routin...

Anti-Osteoporotic Medication-Related Jaw Osteonecrosis: A Descriptive Analysis ...

Congenital Muscular Dystrophy Type 1A: The Role of Multidisciplinary Rehabilita...

Merosinopathy is a subtype of muscular dystrophy with recessive autosomal transmission, resulting from an α2-chain-laminin/merosin deficiency. It affects around 1-9/ 1 000 000 individuals. Classically, it is subdivided in two phenotypic categories: one that is more common and severe, known as congenital muscular dystrophy type 1A, and a lesser common form of mild presentation. Congenital muscular dystrophy type...

IMPACT OF ARTERIAL HYPERTENSION ON COVID-19

Introduction: SARS-CoV-2 binds to host cells through the angiotensin-converting enzyme 2. Several studies have suggested that hypertensive individuals, due to the overexpression of this enzyme in alveolar epithelial cells, may have a higher risk of contracting COVID-19 and having a more serious illness. In fact, arterial hypertension has been described as one of the most frequent comorbidities in patients with ...

IMPACT OF ARTERIAL HYPERTENSION ON HEMORRHAGIC STROKE

Introduction: Cerebrovascular diseases continue to be one of the leading causes of morbidity and mortality worldwide. Although less frequent than ischemic strokes, hemorrhagic strokes have higher mortality rates and have arterial hypertension (AHT) as the main risk factor. Objectives: Analyze the prevalence of AHT in patients hospitalized for hemorrhagic stroke, the demographic characteristics of this populatio...

SARS-COV-2: An Intruder In The Renin-Angiotensin-Aldosterone System

Introduction: The new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses angiotensin-2 converting enzyme (ACE 2) to enter cells. It is theorized that the use of angiotensin converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) would increase this enzyme expression, raising the hypothesis that these drugs increase the susceptibility to coronavirus disease 2019 (COVID-19)...

Referral to a pediatric outpatient Immunology and Allergy consultation at a uni...

Introduction: Allergic diseases are common in pediatric age and their prevalence has increased in recent years. The literature is scarce regarding the referral of pediatric patients to the Allergy and Clinical Immunology outpatient clinic at tertiary hospitals, but this is relevant because, in addition to being responsible for the diagnosis and management of allergic diseases, this specialty mainly provides out...

The frequency of non-motor symptoms in SCA3 and their association with disease ...

Background Non-motor symptoms (NMS) are a substantial burden for patients with SCA3. There are limited data on their frequency, and their relation with disease severity and activities of daily living is not clear. In addition, lifestyle may either influence or be affected by the occurrence of NMS. Objective To characterize NMS in SCA3 and investigate possible associations with disease severity and lifestyle fac...

A standardised protocol for blood and cerebrospinal fluid collection and proces...

The European Spinocerebellar Ataxia Type 3/Machado-Joseph Disease Initiative (ESMI) is a consortium established with the ambition to set up the largest European longitudinal trial-ready cohort of Spinocerebellar Ataxia Type 3/Machado-Joseph Disease (SCA3/MJD), the most common autosomal dominantly inherited ataxia worldwide. A major focus of ESMI has been the identification of SCA3/MJD biomarkers to enable futur...

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