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Diagnosis and Laboratory Follow-Up of Patients with Multiple Myeloma: Guideline...

Pires, Ana Marta; Barreto, João Pedro; Caetano, Joana; Soares, Maria José; Geraldes, Catarina; Fernandes, Bruno; Coucelo, Margarida; Chacim, Sérgio

Multiple myeloma is a neoplasm of plasma cells that in most cases is associated with the secretion of monoclonal immunoglobulins and can involve multiple organs. Its timely diagnosis is essential to limit or avoid irreversible damage and dysfunction of target organs. Appropriate initial stratification of patients allows for optimization in the selection and sequence of therapy, as well as proper follow-up durin...

Date: 2025   |   Origin: Acta Médica Portuguesa

Diagnosis and laboratory follow-up of patients with multiple myeloma: guideline...

Pires, Ana Marta; Barreto, João Pedro; Caetano, Joana; Soares, Maria José; Geraldes, Catarina; Fernandes, Bruno; Coucelo, Margarida; Chacim, Sérgio

Multiple myeloma is a neoplasm of plasma cells that in most cases is associated with the secretion of monoclonal immunoglobulins and can involve multiple organs. Its timely diagnosis is essential to limit or avoid irreversible damage and dysfunction of target organs. Appropriate initial stratification of patients allows for optimization in the selection and sequence of therapy, as well as proper follow-up durin...


Paraparesis Caused by Chronic Lymphocytic Leukemia Mass Compressing the Spinal ...

Marques, Ana João; Almeida Pinto, Mónica; Cunha, Manuel; Taipa, Ricardo; Gabriel, João Paulo

B-cell chronic lymphocytic leukemia (CLL-B) is the commonest adult-onset leukemia. Although extra-medullary disease has been reported, neurological consequences are seldom a concern. We aim to report an unusual case of a 66 years-old woman who developed subacute paraparesis due to dorsal (D2-D6) spinal cord compression by an extradural CLL mass, 2 years after CLL diagnosis.; A leucemia linfocítica crónica tipo ...

Date: 2024   |   Origin: SINAPSE

Accounting in the context of war: the Portuguese case of the ‘Guerra do Ultrama...

Cunha, Manuel; Gomes, Delfina; Caria, Ana; Menezes, Carlos; Ribeiro, João Leite

This study focuses on the period of the Portuguese Overseas War (1961–1974), with the aim of analysing the role of military accounting in Portugal, particularly regarding whether state budgetary procedures were adapted to meet the needs of the state and the military. The analysis was developed by considering the budget constraints faced at the time, which were profoundly influenced by the laws of public sector ...


Was Rooming-In a Safe Approach to Newborns from SARS-Cov-2 Positive Mothers?

Jonet, Joana; Condessa, Luzia; Limbert, Maria; Roquette, Margarida; Tavares, Ana; Cunha, Manuel

Introduction: Since the emergence of coronavirus disease 2019 (COVID-19) there are limited data describing the risks and specific effects of SARS-CoV-2 in pregnant women and their neonates. To date, there is scarce evidence of in utero transmission, and the risk of perinatal transmission and consequent neonate’s risk of developing COVID-19 during the perinatal period are also unknown. Methods: Since April 2020,...


Moderation and moderated mediation in the analysis of non-nutritive sucking pat...

Cunha, Manuel; Diniz, Ana; Barreiros, João

Introduction: Stimulation of non-nutritive suction has been shown to influence the maturation process of nutritive suction. Objective: Analyze the effect of maturation on the suction pattern, mediated by the time of experience. Methods: Sample consisting of 34 newborns with an average gestational age of 33.2 weeks and an average experience time of 14.7 days. We used the suction pattern as a moderation model. Th...


Moderação e mediação na análise do padrão de sucção não nutritiva em recém-nasc...

Cunha, Manuel; Diniz, Ana; Barreiros, João

Introdução: A estimulação da sucção não nutritiva mostrou influenciar o processo de maturação da sucção nutritiva. Objetivo: Analisar o efeito da maturação sobre o padrão de sucção, mediado pelo tempo de experiência. Métodos: Amostra constituída por 34 recém-nascidos com idade gestacional média de 33,2 semanas e tempo médio de experiência de 14,7 dias. Utilizámos o padrão de sucção como modelo de moderação. A v...

Date: 2021   |   Origin: Millenium

Offsetting the Impact of CO2 Emissions Resulting from the Transport of Maiêutic...

Veludo, Guilherme; Cunha, Manuel; Sá, Maria Manuel; Oliveira-Silva, Carla


Recommendation of Charts and Reference Values for Assessing Growth of Preterm I...

Pereira-da-Silva, Luís; Virella, Daniel; Frutuoso, Simão; Cunha, Manuel; Rocha, Gustavo; Pissarra, Susana

The growth charts and reference values for preterm infants are revisited and recommendations for their use updated by the Portuguese Neonatal Society. To assess intrauterine growth: The cross-sectional sex specific Fenton 2013 charts, based on birth weight, length and head circumference, are the most appropriate. Neonates born with weight < 3rd percentile are classified as small-for-gestational age and those bo...


Moderation and moderated mediation in the analysis of non-nutritive sucking pat...

Cunha, Manuel; Barreiros, João; Diniz, Ana; Pereira, José Miguel Costa Dias


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