2 documents found, page 1 of 1
Chemsex in Lisbon? Self-reflexivity to uncover the scene and discuss the creati...
Pires, Cristiana Vale; Gomes, Filipe Couto; Caldas, João; Cunha, MarThis essay is based in a self-reflexive collective process and intends to present the chemsex scene in Lisbon and harm reduction responses implemented to address the needs of chemsex practitioners. The analysis considered professional experiences, participant observation, literature review of the relevant data in Portugal and autoethnographic data from a chemsex practitioner and peer educator. This essay aims t...
Neuronal dynamics and miRNA signaling differ between SH-SY5Y APPSwe and PSEN1 M...
Garcia, Gonçalo; Pinto, Sara; Cunha, Mar; Fernandes, Adelaide; Koistinaho, Jari; Brites, DoraNeuronal miRNA dysregulation may have a role in the pathophysiology of Alzheimer’s disease (AD). miRNA(miR)-124 is largely abundant and a critical player in many neuronal functions. However, the lack of models reliably recapitulating AD pathophysiology hampers our understanding of miR-124’s role in the disease. Using the classical human SH-SY5Y-APP695 Swedish neuroblastoma cells (SH-SWE) and the PSEN1 mutant iP...