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Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocyto...

Rosado-Ramos, Rita; Poças, Gonçalo M.; Marques, Daniela; Foito, Alexandre; M Sevillano, David; Lopes-da-Silva, Mafalda; Gonçalves, Luís G.

Parkinson's Disease (PD) is a common neurodegenerative disorder affecting millions of people worldwide for which there are only symptomatic therapies. Small molecules able to target key pathological processes in PD have emerged as interesting options for modifying disease progression. We have previously shown that a (poly)phenol-enriched fraction (PEF) of Corema album L. leaf extract modulates central events in...


Anything but Conventional Chromatography Approaches in Bioseparation

Roque, Ana Cecília Afonso; Pina, Ana Sofia; Azevedo, Ana Margarida; Aires-Barros, Raquel; Jungbauer, Alois; Di Profio, Gianluca; Heng, Jerry Y. Y.

PTDC/BII-BIO/28878/2017 UIDB/04378/2020 UID/BIO/04565/2020 POCI-01-0145-FEDER-007728 LISBOA-01-0145-FEDER-028878 Future Fellowship (EP/N015916/1) Sem PDF conforme despacho.; While packed bed chromatography, known as conventional chromatography, has been serving the biopharmaceutical industry for decades as the bioseparation method of choice, alternative approaches are likely to take an increasing leading role i...


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