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The influence of temperature on the impacts of caffeine in mussels: evaluating ...

Cunha, Marta; Petrillo, Vincenzo; Madeira, Madalena; He, Yide; Coppola, Francesca; Meucci, Valentina; De Marchi, Lucia; Soares, Amadeu M. V. M.

In aquatic ecosystems, the presence of pharmaceuticals, particularly caffeine (CAF), has been linked to wastewater discharge, hospital waste, and the disposal of expired pharmaceutical products containing CAF. Additionally, rising temperatures due to climate change are anticipated in aquatic environments. This study aimed to assess the toxicity of various CAF concentrations under current (17 °C) and projected (...


Bioactive potential and chromatographic characterization of body mucus from Por...

Cunha, Marta; Coscueta, Ezequiel R.; Brassesco, María Emilia; Almada, Frederico; Gonçalves, David; Pintado, Manuela

The body mucus in fish provides a stable physical or chemical barrier against invading pathogens. In mucus, antimicrobial peptides are secreted as a response to immunestimulation. Studies have shown antimicrobial activity against multidrug­resistant pathogens and low toxicity to eukaryotic cells. Previously, body mucus from five captive Halobatrachus didactylus individuals was collected. We aim to explore the m...


First bioactive characterization of the skin mucus from Portugal coastal fish H...

Cunha, Marta; Coscueta, Ezequiel R.; Brassesco, Maria Emilia; Almada, Frederico; Gonçalves, David; Pintado, Manuela


Peptide fraction identification by SE-HPLC and LC-MS/MS analysis of the body mu...

Cunha, Marta; Coscueta, Ezequiel R.; Brassesco, María Emilia; Almada, Frederico; Gonçalves, David; Pintado, Manuela

The mucus covers the fish's body, working as a protective barrier. Besides physical protection, mucus provides molecules that protect the fish from pathogens damaging. 1,2These include antimicrobial peptides secreted in the mucus, which play an essential role in defense against microbial pathogens since these belong to the innate immune system2,3. In this study, two adult Halobatrachus didactylus individuals we...


First bioactive characterization of the skin mucus from Portugal coastal fish h...

Cunha, Marta; Coscueta, Ezequiel R.; Brassesco, Maria Emilia; Almada, Frederico; Gonçalves, David; Pintado, Manuela

The marine environment has several promising features for the discovery of new molecules. The oceans have half of the planet’s biodiversity and are a harsh environment for aquatic organisms challenging them to have a set of bioactive molecules to survive [1]. It is well known the mucus secreted by fish epidermis works as a defense barrier against harmful elements from the external environment [2]. Therefore, th...


Monitorização de campo de águas subterrâneas

Pereira, Paula; Cunha, Marta; Pinto, Cláudia; Alves, C.; Ribeiro, Vítor

Existem vários exemplos nos estudos geológicos de caraterísticas físicas que são utilizadas para investigar modificações químicas, como seja a massa volúmica (que em séries isomórficas pode mostrar relações aproximadamente lineares com a variação entre dois termos químicos extremos) e a radiação gama que reflete as variações das atividades específicas de radioisótopos. No estudo das águas subterrâneas, vários p...


GeoloGIS-BH: An Information System for Using the Built Heritage for Geological ...

Ribeiro, Vítor; Cunha, Marta; Pereira, Paula; Pinto, Cláudia; Alves, C.

There are examples of using stones of the cultural heritage for teaching purposes. Information systems have found several potential uses in the promotion and preservation of cultural heritage. In this paper is considered the conceptual framework of an information system concerning features of geological interest (FGI) in the built heritage (without any consideration in terms of its software implementation). Thi...


Aplicação em Olaria de Terra Rossa de Vila Viçosa e Borba

Cunha, Marta; Martins, Ruben; Lopes, Luís; Gomes, Celso; Arroz, Maria; Santos, Dulce; Rosado, Francisco

A indústria extractiva de rochas ornamentais carbonatadas produz diferentes tipos de resíduos possuidores de características que permitem ser utilizados em diferentes aplicações a jusante daquela indústria, tornando imprecisa a denominação de “resíduo” graças ao possível enquadramento na designação “subproduto”. A terra rossa resultante da destapação efectuada aquando da abertura de pedreiras em maciços carbona...


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