16 documents found, page 1 of 2
Diagnosis and Laboratory Follow-Up of Patients with Multiple Myeloma: Guideline...
Pires, Ana Marta; Barreto, João Pedro; Caetano, Joana; Soares, Maria José; Geraldes, Catarina; Fernandes, Bruno; Coucelo, Margarida; Chacim, SérgioMultiple myeloma is a neoplasm of plasma cells that in most cases is associated with the secretion of monoclonal immunoglobulins and can involve multiple organs. Its timely diagnosis is essential to limit or avoid irreversible damage and dysfunction of target organs. Appropriate initial stratification of patients allows for optimization in the selection and sequence of therapy, as well as proper follow-up durin...
Diagnosis and laboratory follow-up of patients with multiple myeloma: guideline...
Pires, Ana Marta; Barreto, João Pedro; Caetano, Joana; Soares, Maria José; Geraldes, Catarina; Fernandes, Bruno; Coucelo, Margarida; Chacim, SérgioMultiple myeloma is a neoplasm of plasma cells that in most cases is associated with the secretion of monoclonal immunoglobulins and can involve multiple organs. Its timely diagnosis is essential to limit or avoid irreversible damage and dysfunction of target organs. Appropriate initial stratification of patients allows for optimization in the selection and sequence of therapy, as well as proper follow-up durin...
Manual básico SPSS: como o utilizar de forma rápida e fácil
Sangreman, Carlos; Faria, Raquel; Cunha, NunoCom este manual procura-se explanar um modo rápido e eficaz de utilizar o IBM SPSS Statistics, na introdução, gestão e análise de dados. Ou seja, a forma como a abordagem de dados pode ser realizada no domínio das ciências sociais utilizando a estatística descritiva, desmistificando a sua utilização.
Genetic polymorphisms of P2RX7 but not of ADORA2A are associated with the sever...
Lindo, Jorge; Nogueira, Célia; Soares, Rui; Cunha, Nuno; Almeida, Maria Rosário; Rodrigues, Lisa; Coelho, Patricia; Rodrigues, FranciscoSARS-CoV-2 infection ranges from mild to severe presentations, according to the intensity of the aberrant inflammatory response. Purinergic receptors dually control the inflammatory response: while adenosine A2A receptors (A2ARs) are anti-inflammatory, ATP P2X7 receptors (P2X7Rs) exert pro-inflammatory effects. The aim of this study was to assess if there were differences in allelic andgenotypic frequencies of ...
Outpatient Population of the First Nephrology Liaison Psychiatry Consultation a...
Sousa, Rui; Cunha, NunoIntroduction: The diagnosis of end -stage chronic kidney disease confronts the patient with the need to adjust and acquire coping strategies in the face of the possibility of depending on a dialysis machine for their survival. This period is variable and given the recurrent complications of the chronic kidney disease (CKD), it likely leads to an intermittent and/or chronic adjustment disorder. In this way, our ...
Genetic polymorphisms of P2RX7 but not of ADORA2A are associated with the sever...
Lindo, Jorge; Nogueira, Célia; Soares, Rui; Cunha, Nuno; Almeida, Maria Rosário; Rodrigues, Lisa; Coelho, Patrícia; Rodrigues, FranciscoSARS-CoV-2 infection ranges from mild to severe presentations, according to the intensity of the aberrant inflammatory response. Purinergic receptors dually control the inflammatory response: while adenosine A2A receptors (A2ARs) are anti-inflammatory, ATP P2X7 receptors (P2X7Rs) exert pro-inflammatory effects. The aim of this study was to assess if there were differences in allelic and genotypic frequencies of...
Climb Up Aplicação Móvel para escalada Indoor
Cunha, NunoEste trabalho pretende apresentar o estudo para o desenvolvimento de uma aplicação aplicada ao contexto desportivo, mais propriamente ao Boulder Indoor ou Escalada Indoor, a necessidade de integração de informação de diferentes plataformas motivou a exploração deste tema. O fator novidade também foi tido em conta, uma vez que não existe no mercado nenhum ginásio do sector da escalda com uma aplicação própria. P...
Surveillance of succinate dehydrogenase gene mutation carriers : insights from ...
Martins, Raquel; Cunha, Nuno; Simões, Helder; Matos, Maria João; Silva, João; Torres, Isabel; Rodrigues, Fernando; Leite, Valeriano; Teixeira, Manuel R.Objective: Mutations in the genes coding for succinate dehydrogenase (SDHx) are the most frequent germline alterations in pheochromocytomas and paragangliomas. Evidence for the advantages associated with presymptomatic screening for SDHx mutation carriers is scarce. This study describes a nationwide cohort of these mutation carriers and aims to compare patients with clinical manifestations of the disease and th...
Relação entre género ao nível da motivação para a prática das atividades despor...
Cunha, Nuno; Amante, João; Gomes, Ricardo; Figueira, Ana; Figueiredo, Teresa; Pereira, A; Nunes, Paulo; Santos, Fernando Jorge Lourenço DosOs objetivos do presente estudo foram analisar a motivação para a prática de ativi dades desportivas entre homens e mulheres e fatores que conduzem ao envolvi mento nas atividades. Participaram no estudo 20 homens (34.55±16.30 anos de idade) e 20 mulheres (30.05±12.70 anos de idade). Foi utilizado o Questionário de Motivação para as Atividades Desportivas (QMAD) (Serpa & Frias,1990). Com posto por 30 perguntas ...
Metabolomic urine profile : searching for new biomarkers of SDHx-associated phe...
Martins, Raquel; Gonçalves, Luís G; Cunha, Nuno; Bugalho, Maria JoãoContext: Metabolomic studies of pheochromocytoma and paraganglioma tissue showed a correlation between metabolomic profile and presence of SDHx mutations, especially a pronounced increase of succinate. Objective: To compare the metabolomic profile of 24-hour urine samples of SDHx mutation carriers with tumors (affected mutation carriers), without tumors (asymptomatic mutation carriers), and patients with sporad...