The pain perception represents an important adapting mechanism based on the nociceptive system function, which depends on the excitability of the nervous system, thus, searching new methods of control for the excitability in the nociceptive system is very important for the human analgesia. Objective: To determine the excitation threshold of nociceptive system in mice treated with different doses of magnesium ch...
Ethnopharmacological relevance: Calycophyllum spruceanum (Benth.) Hook. F. ex K. Schum. is widely distributed in the Amazonian region of Brazil, where it is popularly known as “mulateiro”, “pau-mulato”, “pau-mulato-devárzea”, “escorrega-macaco” or “pau-marfim”. Preparations of C. spruceanum barks are used in the form of tea, poultice or skin patches to treat stomach diseases, skin inflammation and uterus tumors...
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