Over the last few years, several cases of statin-induced necrotizing myopathy have been described. This myopathy is characterized by the necrosis of muscle fibers and the presence of anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase (anti-HMGCR) antibodies. Although the diagnosis of myopathies relies on muscle biopsy, which is considered the gold-standard, the search for autoantibodies has proved to be an es...
Introduction: Screening for autoantibodies in HEp-2 cells by indirect immunofluorescence is currently accepted as the gold-standard test for the diagnosis of systemic autoimmune diseases. The main objective of the International Consensus on ANA Patterns is to achieve a consensus on the nomenclature and description of antinuclear antibody morphological patterns. This work aims to build on the International Conse...
Introduction: Screening for autoantibodies in HEp-2 cells by indirect immunofluorescence is currently accepted as the gold-standard test for the diagnosis of systemic autoimmune diseases. The main objective of the International Consensus on ANA Patterns is to achieve a consensus on the nomenclature and description of antinuclear antibody morphological patterns. This work aims to build on the International Conse...
Teachers, school psychologists, learners and their families are facing new challenges. The purpose of this study was to analyse Portuguese teachers’ perceptions of the demands they feel respectively to their educational practices. Participants (N = 178) included private schools teachers from preschool through secondary school. Data were collected through an anonymous questionnaire composed of open-ended questio...
Este estudo teve como objetivo analisar as preocupações relatadas por educadores/professores, relativamente à sua experiência diária enquanto profissionais docentes. Participaram na investigação 178 educadores e professores de estabelecimentos de ensino privado em Portugal, do pré-escolar ao 12.º ano. Os dados foram recolhidos através de um questionário com questões abertas, cujas respostas foram analisadas atr...