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Levothyroxine Replacement Improves Oxidative Status in Primary Hypothyroidism
Masullo, Laís Farias; Magalhães, Rejane Araújo; Lemes, Romélia Pinheiro Gonçalves; Almeida Filho, Tarcísio Paulo de; Castro, Marilena Facundo deObjective: Although hypothyroidism has been linked to oxidative stress, data regarding the relationship between thyroid hormone levels and oxidative stress is still inconsistent. This study was designed to evaluate the effect of levothyroxine replacement on oxidative stress in women with primary hypothyroidism. Design: A total of 25 female patients with primary hypothyroidism were included. Oxidative stress mar...
Avaliação imuno-histoquímica da expressão de receptor de estrógeno β no carcino...
Cunha, Tainá Osterno VasconcelosDifferentiated thyroid cancer (DTC) is one of the most prevalent neoplasms and its incidence has increased in the last decades. The higher incidence of DTC in women of childbearing age suggests a possible involvement of hormonal factors in their pathophysiology. Estrogen influences the proliferation of neoplastic cells through the activation of its alpha (REα) and beta (REβ) receptors. REα promotes cell prolife...