5 documents found, page 1 of 1
Gasdermin D inhibition prevents multiple organ dysfunction during sepsis by blo...
Silva, Camila Meirelles S.; Wanderley, Carlos Wagner S.; Veras, Flavio P.; Sonego, Fabiane; Nascimento, Daniele C.; Gonçalves, Augusto V.Made available in DSpace on 2022-04-29T08:46:05Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-12-23; Multiple organ dysfunction is the most severe outcome of sepsis progression and is highly correlated with a worse prognosis. Excessive neutrophil extracellular traps (NETs) are critical players in the development of organ failure during sepsis. Therefore, interventions targeting NET release would likely...
Neural Infection by Oropouche Virus in Adult Human Brain Slices Induces an Infl...
Almeida, Glaucia M.; Souza, Juliano P.; Mendes, Niele D.; Pontelli, Marjorie C.; Pinheiro, Nathalia R.; Nogueira, Giovanna O.; Cardoso, Ricardo S.Made available in DSpace on 2022-04-29T08:46:10Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-11-23; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Apoio ao Ensino, Pesquisa e Assistência do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo; Fundação de Amp...
Toxicity of spike fragments SARS-CoV-2 S protein for zebrafish: A tool to study...
Ventura Fernandes, Bianca H.; Feitosa, Natália Martins; Barbosa, Ana Paula; Bomfim, Camila Gasque; Garnique, Anali M.B.; Rosa, Ivana F. [UNESP]Made available in DSpace on 2022-04-29T08:46:15Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-03-20; Ministério da Ciência, Tecnologia e Inovação; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Despite the significant increase in the generation of SARS-CoV-2 contaminated domestic and hospital wastewater, little is kno...
15d-PGJ(2)-loaded nanocapsules ameliorate experimental gout arthritis by reduci...
Ruiz-Miyazawa, Kenji W.; Staurengo-Ferrari, Larissa; Pinho-Ribeiro, Felipe A.; Fattori, Victor; Zaninelli, Tiago H.; Badaro-Garcia, StephanieMade available in DSpace on 2018-11-26T17:55:27Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-09-18; Pesquisa para o Sistema Unico de Saude (PPSUS) grant from Departamento de Ciencia e Tecnologia da Secretaria de Ciencia, Tecnologia e Insumos Estrategicos, Ministerio da Saude (Decit/SCTIE/MS, Brazil); Fundacao Araucaria and Secretaria Estadual de Saude, Parana (SESA-PR, Brazil); Fundação de Amparo à Pe...
The adaptor protein myd88 is a key signaling molecule in the pathogenesis of ir...
Wong, Deysi V. T.; Lima-Júnior, Roberto C. P.; Carvalho, Cibele B. M.; Borges, Vanessa F.; Wanderley, Carlos W. S.; Bem, Amanda X. C.Intestinal mucositis is a common side effect of irinotecan-based anticancer regimens. Mucositis causes cell damage, bacterial/endotoxin translocation and production of cytokines including IL–1 and IL–18. These molecules and toll-like receptors (TLRs) activate a common signaling pathway that involves the Myeloid Differentiation adaptor protein, MyD88, whose role in intestinal mucositis is unknown. Then, we evalu...