4 documents found, page 1 of 1
Development of a lethal model of peritonitis for assessment of laparoscopic and...
Salgado Júnior,Wilson; Santos,José Sebastião dos; Cunha,Fernando de QueirozPURPOSE: Development of a lethal model of peritonitis to assess the results of treating that peritonitis using videolaparoscopy and laparotomy. METHODS: We developed a model of peritonitis in rats using cecal ligation (CLP) against a 2-mm diameter rigid mold and puncture. Two experiments were performed: determination of seven-day lethality; and analysis of white cell counts, blood cultures and cytokines (Interl...
Effect of myocardial protection and perfusion temperature on production of cyto...
Tavares-Murta,Beatriz Martins; Cordeiro,Adriana Oliveira; Murta,Eddie Fernando Candido; Cunha,Fernando de Queiroz; Bisinotto,Flora Margarida BarraPURPOSE: To investigate the effects of different conditions used during cardiopulmonary bypass (CPB) surgery on accompanying production of cytokine and nitric oxide (NO). METHODS: Patients undergoing CPB for the first time were prospectively enrolled and divided into two groups according to CPB parameters performed: i) normothermia (36.5-37°C) with blood cardioplegia (NB group, n=10) and ii) hypothermia (29-31°...
Effect of acupuncture on TNF-alpha, IL-1b and IL-10 concentrations in the perit...
Scognamillo-Szabó,Márcia Valéria Rizzo; Bechara,Gervásio Henrique; Cunha,Fernando de QueirozAcupuncture is an ancient and empirical therapeutic procedure known by its efficacy in the treatment of pain. However, the influence of acupuncture on inflammatory process is still poorly understood and additional research is needed. In this work, we investigated the mechanism of action of manual acupuncture on the inhibition of neutrophil migration to the peritoneal cavity induced by the inflammatory stimulus ...
Efeito de inibidores da sintase de óxido nítrico na dor inflamatória articular ...
Rocha,Francisco Airton Castro da; Rocha,José Carlos da Silva; Peixoto,Magno Eric Barbosa; Jancar,Sonia; Cunha,Fernando de QueirozOBJETIVO: Investigar o papel do óxido nítrico (NO) no influxo celular (IC) e a incapacitação articular (IA) na artrite por zymosan (AZy). MÉTODOS: Ratos Wistar receberam injeção de Zy (1mg) no joelho direito. Grupos-controles receberam salina. A IA foi avaliada pelo Teste de incapacitação articular para ratos. Após sacrifício, o IC e a liberação de PGE2 foram avaliados no lavado articular. Avaliou-se o edema pe...