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Neurofibromatosis: part 2 – clinical management

Batista,Pollyanna Barros; Bertollo,Eny Maria Goloni; Costa,Danielle de Souza; Eliam,Lucas; Cunha,Karin Soares Gonçalves; Cunha-Melo,José Renan

Part 1 of this guideline addressed the differential diagnosis of the neurofibromatoses (NF): neurofibromatosis type 1 (NF1), neurofibromatosis type 2 (NF2) and schwannomatosis (SCH). NF shares some features such as the genetic origin of the neural tumors and cutaneous manifestations, and affects nearly 80 thousand Brazilians. Increasing scientific knowledge on NF has allowed better clinical management and reduc...

Date: 2015   |   Origin: Oasisbr

Zimography is an effective method for detection of matrix metalloproteinase 2 (...

Lisboa,Rodolfo Assis; Andrade,Marcus Vinícius; Cunha-Melo,José Renan

PURPOSE: To describe a method to characterize the gelatinase activity of cultured human periodontal fibroblasts stimulated with Pam3Cys and E. coli LPS, ligands of TLR2 and TLR4 respectively, and by centrifugation of the cultures, simulating an orthodontic force. METHODS: To study MMP-2 activity, primary cultures of human periodontal fibroblasts were stimulated with the addition of TLRs 2 and 4 ligands and the ...

Date: 2013   |   Origin: Oasisbr

Cirurgia não ginecológica em pacientes com câncer de ovário

Silva-Filho,Agnaldo Lopes da; Cândido,Eduardo Batista; Noviello,Maurício Bechara; Santos-Filho,Admário Silva; Traiman,Paulo; Triginelli,Sérgio Augusto

OBJETIVO: avaliar a freqüência da utilização de procedimentos cirúrgicos não ginecológicos no tratamento do câncer de ovário, assim como descrever as suas complicações. MÉTODOS: foram incluídas retrospectivamente 82 pacientes, atendidas no período de fevereiro de 1999 a outubro de 2003, e que haviam sido submetidas a laparotomia para tratamento cirúrgico do câncer de ovário. Foram incluídas no estudo apenas pac...

Date: 2004   |   Origin: Oasisbr

Animal model of the abdominal compartment syndrome as a single insult and as a ...

Rezende-Neto,João Baptista de; Silva,Alcino Lázaro da; Cunha-Melo,José Renan

The objective of this paper was to develop a clinically relevant abdominal compartment syndrome experimental model, as a single insult and as a second insult flowing hemorrhagic shock. In the single insult model, Sprague-Dawley male-rats are anesthetized, invasively monitored (central venous pressure and mean arterial pressure), and mechanically ventilated during intraperitoneal injection of air to provoke the ...

Date: 2003   |   Origin: Oasisbr

Perianal fistula: retrospective study of surgical treatment of 241 cases

Drager,Luciano Ferreira; Andrade,Miriam Nogueira Barbosa; Conceição,Sérgio Alexandre; Cunha-Melo,José Renan

Perianal fistula, usually has a criptoglandular etiology, developing from a perianal abscess and communicating the anal mucosa with the perianal skin. The aim of this paper is to study retrospectively 241 cases of perianal fistula (172 men and 69 women; 2,5:1) aging from 7 and 80 years old (average: 37,4 years), operated on at the Hospital da Clínicas - UFMG, from 1977 to 1996. The surgical techniques and post-...

Date: 1998   |   Origin: Oasisbr

THE MOUSE AS AN EXPERIMENTAL MODEL FOR TITYUS SERRULATUS SCORPION ENVENOMING

Magalhães,Mônica de Mônico; Viana,Gisele; Arantes,Rosa Maria Esteves; Santos,Tasso Moraes; Cunha-Melo,José Renan

The scorpion toxin induces a number of physiological parameters alterations, as disturbance of cardiac rhythm, heart failure, shock, pancreatic hypersecretion, abortion, respiratory arrhytmias and pulmonary edema. As the purification of the venom fractions is a laborious process, one alternative for this would be the utilization of small animals. We utilized in the present study thity-six mice that received pro...

Date: 1998   |   Origin: Oasisbr

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