CONTEXTO: Os pacientes com esquizofrenia (SCZ) apresentam anomalias importantes no metabolismo lipídico e da glicose, que podem ser induzidas pela terapia antipsicótica (AP) e pelo estilo de vida associado. O risco de doenças cardiovasculares, diabetes mellitus e síndrome metabólica está aumentado nestes pacientes, que apresentam taxa de mortalidade por doenças cardiovasculares duas vezes mais elevada do que a ...
INTRODUCTION: Day hospitals in psychiatry are a major alternative to inpatient care today, acting as key components of community and social psychiatry. Objective: To study trends in the use of psychiatric day hospitals over the last decades of the 20th century and the first decade of the 21st century, focusing on patient age, sex, and diagnostic group, using data from Centro Hospitalar São João, Porto, Portugal...
Background: Sleep disorders can be related to loss, disruption or inappropriate day-night rhythm of sleep and represent a great economic burden, involving morbidity and mortality. The insomnia or hypersomnia, secondary to a psychiatric disorder such as depression or psychosis, is frequent in psychiatric practice. Moreover, although uncommon, primary sleep disorders can also cause psychological or psychiatric pr...
Unipolar mania, also referred as recurrent mania or unipolar recurrent mania, is an entity which position in bipolar disorder remains controversial. Notwithstanding, there are a considerable number of bipolar patients in clinical practice presenting only with recurrent episodes of mania or hypomania, without episodes of depression. Additionally, the existence of certain clinical, demographic and treatment pecul...
The Day Hospital constitutes one of the main components of the community psychiatry and it is integrated in the current social psychiatry policy, representing one of the main alternatives to inpatient regimen. The concept was created in Russia in the 1930s and spread to America during the 40s and 50s, reaching its peak in the 1970s. Even though there was in the decades ahead a decline of expansion and an in...
A clozapina é um antipsicótico que confere benefícios clínicos significativos na esquizofrenia resistente. Os efeitos adversos como leucopenia, sedação, aumento de peso, geralmente são aparentes nas fases iniciais do tratamento com clozapina, e raramente se observam efeitos extra-piramidais, discinésia tardia ou aumento da prolactina. Um dos efeitos adversos descritos é a ocorrência de crises epilépticas (miocl...