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Severe Acute Hepatitis E in a Woman with an Autoimmune Background

Nascimento, M; Almeida-Santos, M; Fernandes, M; Maltez, F; Lino, S; Curran, M; Mesquita, J

Hepatitis E virus genotype 3 infections are normally asymptomatic in immunocompetent individuals. Symptomatic cases of acute icteric hepatitis E are seldom observed among women, younger men and children but are particularly seen in middle-aged/elderly men. We report a case of severe acute hepatitis E caused by genotype 3 in an immunocompetent 40-year-old woman that required prolonged hospitalization. Her medica...


Hepatitis E Virus Genotype 1 Cases Imported to Portugal from India, 2016

Mesquita, JR; Almeida-Santos, M; Fernandes, M; Maltez, F; Lino, S; Alves, L; Abreu-Silva, J; Oliveira, R; Curran, M; Nascimento, M

Hepatitis E in industrialized countries is mainly associated with genotype 3 hepatitis E virus (HEV) and normally causes a sporadic self-limiting disease in immunocompetent individuals. Unlike genotype 3, genotypes 1 and 2 circulate in developing countries, produce severe disease and occur in the epidemic form. Hepatitis E occurring in travellers returning from endemic areas in developing countries is not a nov...


Improving Influenza Surveillance in Portuguese Preschool Children by Parents' R...

Paixão, P; Piedade, C; Papoila, AL; Caires, I; Pedro, C; Santos, M; Silvestre, MJ; Brum, L; Nunes, B; Guiomar, R; Curran, M; Carvalho, A; Marques, T

Influenza surveillance is usually based on nationally organized sentinel networks of physicians and on hospital reports. This study aimed to test a different report system, based on parents' phone contact to the research team and in home collection of samples by a dedicated team. The identification of influenza and other respiratory viruses in children who attended a Hospital Emergency Department was also recor...


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