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Curcumin generates oxidative stress and induces apoptosis in adult schistosoma ...

De Aguiar, Daniela Paula; Moscardini, Mayara Brunetto Moreira; Morais, Enyara Rezende; De Paula, Renato Graciano; Ferreira, Pedro Manuel; Afonso, Ana

Inducing apoptosis is an interesting therapeutic approach to develop drugs that act against helminthic parasites. Researchers have investigated how curcumin (CUR), a biologically active compound extracted from rhizomes of Curcuma longa, affects Schistosoma mansoni and several cancer cell lines. This study evaluates how CUR influences the induction of apoptosis and oxidative stress in couples of adult S. mansoni...


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