32 documents found, page 1 of 4
On polling directions for randomized direct-search approaches: application to b...
Rocha, H.; Dias, J.
An automated bi‐level optimization approach for IMRT
Carrasqueira, P.; Alves, M. J.; Dias, J. M.; Rocha, H.; Ventura, T.; Ferreira, B. C.; Lopes, M. C.Intensity-modulated radiation therapy is used worldwide to treat cancer patients. The objective of this treat-ment is to deliver a prescribed radiation dose to the tumor while sparing, as much as possible, all the healthytissues, especially organs at risk (OAR). This means that the planning of a radiotherapy treatment shouldtake into consideration conflicting objectives: to be able to spare as much as possible t...
An automated treatment planning strategy for highly noncoplanar radiotherapy ar...
Carrasqueira, P.; Rocha, H.; Dias, J. M.; Ventura, T.; Ferreira, B. C.; Lopes, M. C.Radiation therapy is a technology-driven cancer treatment modality that has experienced significant advances over the last decades, due to multidisciplinary contributions that include engineering and computing. Recent technological developments allow the use of noncoplanar volumetric modulated arc therapy (VMAT), one of the most recent photon treatment techniques, in clinical practice. In this work, an automate...
An automated bi‐level optimization approach for IMRT
Carrasqueira, P.; Alves, M. J.; Dias, J. M.; Rocha, H.; Ventura, T.; Ferreira, B. C.; Lopes, M. C.Intensity-modulated radiation therapy is used worldwide to treat cancer patients. The objective of this treatment is to deliver a prescribed radiation dose to the tumor while sparing, as much as possible, all the healthy tissues, especially organs at risk (OAR). This means that the planning of a radiotherapy treatment should take into consideration conflicting objectives: to be able to spare as much as possible...
Distribution and genetic diversity of tomato-infecting begomoviruses in Brazil
Ambrozevícius, L. P.; Calegario, R. F.; Fernandes, J. J.; Mello, R. N. de; Zerbini, F. M.; Ribeiro, S. G.; Ávila, A. C.; Bezerra, I. C.; Lima, M. F.Tomato-infecting begomoviruses have been reported throughout Brazil since the introduction of the B biotype of Bemisia tabaci. Here, we report a large scale survey on the distribution and genetic diversity of tomato-infecting begomoviruses. Tomato samples with typical begomovirus symptoms were collected in seven different states, comprising the major tomato growing areas of the country. Viruses were detected by...
Early prediction of durum wheat yield in Spain using radial basis functions int...
Rocha, H.; Dias, J. M.Durum wheat is an important crop in semi-arid Mediterranean regions as Andalusia, an autonomous community in the southern part of Spain. Accurate early predictions of durum wheat yield can provide precious information for within-season adjustment of crop managing as well as for economical and political stakeholders. In this study, an alternative methodology to mechanistic crop models is proposed for within-seas...
On the growth of Iberian firms: An empirical analysis
Pascoal, R.; Dinis, Augusto M.; Rocha, H.The growth dynamics of firms have been object of numerous studies by econophysicists. The vast majority of these studies was done for large developed countries including the United States of America (US), France and Italy. These studies were conducted for countries with strong economies and whose business fabric has different characteristics from countries such as Portugal or Spain, with more large-sized firms ...
Integrative approaches for the diagnosis of inborn errors of metabolism
Rocha, H.Inborn errors of metabolism (IEM) are a group of inherited genetic disorders affecting Human metabolism. Several examples will be presented illustrating the integration of the diagnostic approaches for different disease groups.
Inequality measures for wealth distribution: Population vs individuals perspective
Pascoal, R.; Rocha, H.Economic inequality is, nowadays, frequently perceived as following a growing trend with impact on political and religious agendas. However, there is a wide range of inequality measures, each of which pointing to a possibly different degree of inequality. Furthermore, regardless of the measure used, it only acknowledges the momentary population inequality, failing to capture the individuals evolution over time....
Molecular picture of cobalamin C/D defects before and after newborn screening era
Nogueira, C.; Marcão, A.; Rocha, H.; Sousa, C.; Fonseca, H.; Valongo, C.; Vilarinho, L.Objective: Birth prevalence of Cobalamin (Cbl) C or D defects in Portugal is an estimated 1:85,000, one of the highest worldwide. We compared the genotype/phenotype of patients identified with CblC or CblD before and after the implementation of expanded newborn screening. Methods: Twenty-five Portuguese CblC/D patients, 14 symptomatic and 11 identified through screening, were diagnosed using gas chromatography ...