4 documents found, page 1 of 1
Supramolecular assembly of multi-purpose tissue engineering platforms from huma...
Ladeira, Bruno; Gomes, Maria; Wei, Kongchang; Custódio, Catarina; Mano, JoãoRecapitulating the biophysical and biochemical complexity of the extracellular matrix (ECM) remains a major challenge in tissue engineering. Hydrogels derived from decellularized ECM provide a unique opportunity to replicate the architecture and bioactivity of native ECM, however, they exhibit limited long-term stability and mechanical integrity. In turn, materials assembled through supramolecular interactions ...
Um caso de Carcinoma do Pulmão de Não Pequenas Células EGFR
Campos, Sofia; Custódio, Catarina; Felizardo, Margarida; Calha, Jaime; Madureira, Rosa Maria; Teixeira, José AlbertoBackground: EGFR mutation is the most frequent in Non-Small Cell Lung Cancer and occurs mainly in women and non-smoking patients. Clinical case: We present the case of a 51-year-old female, former light smoker, diagnosed with lung adenocarcinoma in 2014, in stage IB. She underwent surgery and adjuvant therapy. She recurred after two years with metas-tatic lung and bone disease, with EGFR exon 21 mutation. Thera...
Self-assembly of platelet lysates proteins into microparticles by unnatural dis...
Gomes, Maria C.; Pinho, Ana Rita; Custódio, Catarina; Mano, João F.There is a demand to design microparticles holding surface topographies while presenting inherent bioactive cues for applications in the biomedical and biotechnological fields. Using the pool of proteins present in human-derived platelet lysates (PL), it is reported the production of protein-based microparticles via a simple and cost-effective method, exploring the prone redox behavior of cysteine (-SH) amino a...
Nutritional intake and training load of professional female football players du...
Leão, César; Mendes, António Pedro; Custódio, Catarina; Ng, Mafalda; Ribeiro, Nuno; Loureiro, Nuno; Araújo, João Pedro; Afonso, JoséFootball (soccer) is a high-intensity intermittent sport with large energy demands. In a repeated-measures design, we analysed the nutritional intake and training load of fourteen female football players (22.50 ± 4.38 y; 57.23 ± 8.61 kg; 164 ± 6.00 cm; 18.33 ± 2.48% of fat mass and 23.71 ± 2.51 kg of muscle mass) competing in the highest female Football Portuguese League across a typical mid-season microcycle. ...