24 documents found, page 1 of 3
Influence of spironolactone on matrix metalloproteinase-2 in acute decompensate...
Ferreira, J.; Santos, M.; Oliveira, J.; Marques, I.; Bettencourt, P.; Cyrne-Carvalho, H.Matrix metalloproteinases (MMPs) are a family of enzymes important for the resorption of extracellular matrices, control of vascular remodeling and repair. Increased activity of MMP2 has been demonstrated in heart failure, and in acutely decompensated heart failure (ADHF) a decrease in circulating MMPs has been demonstrated along with successful treatment.
High-Sensitivity Troponin T: A Biomarker for Diuretic Response in Decompensated...
Ferreira, J.; Santos, M.; Almeida, S.; Marques, I; Bettencourt, P.; Cyrne-Carvalho, H.Background. Patients presenting with acutely decompensated heart failure (ADHF) and positive circulating cardiac troponins were found to be a high-risk cohort. The advent of high-sensitive troponins resulted in a detection of positive troponins in a great proportion of heart failure patients. However, the pathophysiological significance of this phenomenon is not completely clear. Objectives. The aim of this stu...
High Sensitivity Troponin T: A Biomarker of Ventricular Wall Stress in Acutely ...
Ferreira, J.; Santos, M.; Almeida, S.; Marques, I.; Bettencourt, P.; Cyrne-Carvalho, H.
Mineralocorticoid receptor antagonism in acutely decompensated chronic heart fa...
Ferreira, J.P.; Santos, M.; Almeida, S.; Marques, I.; Bettencourt, P.; Cyrne-Carvalho, H.
Mineralocorticoid Receptor Antagonism in Acutely Decompensated Chronic Heart Fa...
Ferreira, J.; Santos, M.; Almeida, S.; Marques, I.; Bettencourt, P.; Cyrne-Carvalho, H.
Tailoring diuretic therapy in acute heart failure: insight on early diuretic re...
Ferreira, J.; Santos, M.; Almeida, S.; Marques, I.; Bettencourt, P.; Cyrne-Carvalho, H.
Triple, simultaneous, very late coronary stent thrombosis
Silva-Vieira, M.; Luz, A.; Anjo, D.; Antunes, N.; Santos, M.; Cyrne-Carvalho, H.; Torres, S.Abstract Coronary artery stent thrombosis is an uncommon but potentially catastrophic complication. The risk of very late stent thrombosis (VLST) raises important safety issues regarding the first generation of drug-eluting stents (DES). Although several complex mechanisms for VLST have been suggested and various predictors have been described, its pathophysiology is not completely understood and it is not know...
Tailoring diuretic therapy in acute heart failure: insight on early diuretic re...
Ferreira, J.P.; Santos, M.; Almeida, S.; Marques, I.; Bettencourt, P.; Cyrne-Carvalho, H.
Coronary artery fistula presenting as unstable angina
Silva-Vieira, M.; Antunes, M.; Anjo, D.; Palma, P.; Cyrne-Carvalho, H.; Torres, S.
Mineralocorticoid receptor antagonism in acutely decompensated chronic heart fa...
Ferreira, J.; Santos, M.; Almeida, S.; Marques, I.; Bettencourt, P.; Cyrne-Carvalho, H.Spironolactone was likely to provide faster congestion relief. -------------------------------------------------------------------------------- Abstract Background/objectives Mineralocorticoid receptor antagonist (MRA) use in acutely decompensated chronic heart failure (ADCHF) may improve congestion through diuretic effect and prevent neurohormonal activation. We aimed to evaluate the clinical effect and safety...