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Tadalafil protector effect during ischemia-reperfusion in rats
Wietzikoski,Eduardo Gabriel Gerber; Foiatto,Julio Cesar; Czeczko,Nicolau Gregori; Malafaia,Osvaldo; Koleski,Fernando Cesar; Mierzwa,Tiago CesarAbstract Purpose: To evaluate histological parameters in rat renal tissue after tadalafil use during hot ischemia for 45 minutes and reperfusion for 24 hours. Methods: Twenty rats were divided into 2 groups. In the experimental group 10 mg/kg of tadalafil was used per gavage before the procedure. All cases underwent left partial nephrectomy, followed by 45 minutes of warm ischemia. Left nephrectomy of the remai...
Schinus terebinthifolius raddi (Aroeira) and Orbignya phalerata mart. (Babassu)...
Scheibe,Christian Lamar; Ribas-Filho,Jurandir Marcondes; Czeczko,Nicolau Gregori; Malafaia,Osvaldo; Barboza,Luiz Eduardo DurãesABSTRACT PURPOSE: To evaluate the effect of Schinus terebinthifolius Raddi (aroeira) and Orbignya phalerata Mart. (babassu) in the healing process of cecorrhaphy in rats. METHODS : Fifty four rats were used, distributed into three groups randomly: aroeira, babassu and control, which were divided into three subgroups (six animals) according to the time of the deaths (7, 14, 21 days). All underwent the same surgi...
Ventral abdominal wall defect correction in rats with contaminated meshes
Varella,Paola Zarur; Czeczko,Nicolau Gregori; Prestes,Manoel Alberto; Czeczko,Alexandre Eduardo Augustin; Fagundes,Marília da CruzABSTRACT PURPOSE: To investigate whether there is a difference between Marlex(r) and Dynamesh PP-light Marlex(r) meshes, in the abdominal wall defect correction, on rats in contaminated surgical site. METHODS: Twenty-eight Wistar rats were divided into two groups of 14, and four subgroups of seven animals. All subgroups underwent similar surgical procedure. One group received the mesh Marlex(r) and the other Dy...
Influence of chlorpromazine on renal histology of rats submitted to ischemia an...
Foiatto,Júlio César; Czeczko,Nicolau Gregori; Wietzikoski,Eduardo Gabriel Guerber; Malafaia,Osvaldo; Brenny Filho,Thadeu; Oliveira,André Matos deABSTRACT PURPOSE: To analyze the influence of chlorpromazine on renal histology of rats submitted to ischemia and reperfusion injury. METHODS: Sixteen Wistar rats - split in two groups - have been used: control group, receiving 3 mg/kg isotonic saline solution through caudal vein, and, the chlorpromazine group, receiving 3 mg/kg-IV of such medication. The nephrectomy of the left kidney lower third was carried o...
Osteoarthritis model induced by intra-articular monosodium iodoacetate in rats ...
Morais,Sebastião Vieira de; Czeczko,Nicolau Gregori; Malafaia,Osvaldo; Ribas Filho,Jurandir Marcondes; Garcia,João Batista Santos; Miguel,Marcelo TizzotABSTRACT PURPOSE: To evaluate the usefulness of a knee osteoarthritis model through functional, radiological and microscopic changes of the synovial membrane. METHODS: Forty eight rats were divided randomly into two groups. The first received 0.9% saline in the joint and corresponded to the control group. The second was submitted to experimental osteoarthritis of the right knee induced by monosodium iodoacetate...
Histological evaluation of capsules formed by silicon implants coated with poly...
Silva,Eduardo Nascimento; Ribas-Filho,Jurandir Marcondes; Czeczko,Nicolau Gregori; Pachnicki,Jan Pawel Andrade; Netto,Mário Rodrigues MontemorABSTRACT PURPOSE: To assess the capsules formed by silicone implants coated with polyurethane foam and with a textured surface. METHODS: Sixty-four Wistar albinus rats were divided into two groups of 32 each using polyurethane foam and textured surface. The capsules around the implants were analyzed for 30, 50, 70 and 90 days. Were analyzed the following parameters: foreign body reaction, granulation tissue, pr...
Evaluation of liver regeneration diet supplemented with omega-3 fatty acids: ex...
Silva,Rosilda Mendes da; Malafaia,Osvaldo; Torres,Orlando Jorge Martins; Czeczko,Nicolau Gregori; Marinho Junior,Carlos HespanhaObjective: to evaluate liver regeneration in rats after partial hepatectomy of 60% with and without action diet supplemented with fatty acids through the study of the regenerated liver weight, laboratory parameters of liver function and histological study. Methods: thirty-six Wistar rats, males, adults were used, weighing between 195 and 330 g assigned to control and groups. The supplementation group received t...
DEVELOPMENT OF METRICS FOR TECHNICAL PRODUCTION: QUALIS BOOKS AND BOOK CHAPTERS
Ribas-Filho,Jurandir Marcondes; Malafaia,Osvaldo; Czeczko,Nicolau Gregori; Ribas,Carmen A. P. Marcondes; Nassif,Paulo Afonso NunesObjective: To propose metrics to qualify the publication in books and chapters, and from there, establish guidance for the evaluation of the Medicine III programs. Method: Analysis of some of the 2013 area documents focusing this issue. Were analyzed the following areas: Computer Science; Biotechnology; Biological Sciences I; Public Health; Medicine I. Results: Except for the Medicine I, which has not adopted t...
Efeito de Schinus terebinthifolius Raddi (aroeira) e Carapa guianensis Aublet (...
Santos,Orlando José dos; Malafaia,Osvaldo; Ribas-Filho,Jurandir Marcondes; Czeczko,Nicolau Gregori; Santos,Rayan Haquim PinheiroRACIONAL: A gastrorrafia isolada ou associada ao uso de adesivos biológicos constituiu ao longo da história da cirurgia a forma usual de promover a cicatrização nas lesões gástricas; entretanto, o uso de fitoterápico tem sido cada vez mais empregado para auxiliar o processo cicatrical. OBJETIVO: Avaliar a cicatrização de ferida provocada no estômago de ratos com uso do extrato hidroalcoólico de Schinus terebint...
Comparative study between polypropylene and polypropylene/poliglecaprone meshes...
Utrabo,Carlos Alberto Lima; Czeczko,Nicolau Gregori; Busato,Cesar Roberto; Montemor-Netto,Mario Rodrigues; Malafaia,Osvaldo; Dietz,Ulrich AndreasPURPOSE: To evaluate the healing process of a defect in the ventral abdominal wall of rats, comparing the polypropylene and polypropylene/poliglecaprone meshes on the 30th and 60th postoperative day. METHODS: Thirty two Wistar rats were submitted to a ventral abdominal wall defect, with integrity of the parietal peritoneum. In the repair, were used polypropylene (group A) and polypropylene/poliglecaprone (group...