5 documents found, page 1 of 1
Metal-biosurfactant complexes characterization: binding, self-assembly and inte...
Janek, Tomasz; Rodrigues, L. R.; Gudiña, Eduardo J.; Czyznikowska, ZanetaStudies on the specific and nonspecific interactions of biosurfactants with proteins are broadly relevant given the potential applications of biosurfactant/protein systems in pharmaceutics and cosmetics. The aim of this study was to evaluate the interactions of divalent counterions with the biomolecular anionic biosurfactant surfactin-C15 through molecular modeling, surface tension and dynamic light scattering ...
Biomolecular interactions of lysosomotropic surfactants with cytochrome c and i...
Janek, Tomasz; Czelen, Przemyslaw; Gudiña, Eduardo José; Rodrigues, L. R.; Czyznikowska, ZanetaThe molecular interactions between two single-chain lysosomotropic surfactants DMM-11 (2-Dodecanoyloxyethyl)trimethylammonium bromide) and DMPM-11 (2-Dodecanoyloxypropyl)trimethylammonium bromide) with a small heme-protein (cytochrome c (cyt-c)) in Hepes buffer (pH = 7.4) were extensively investigated by surface tension, dynamic light scattering (DLS), circular dichroism (CD) and fluorescence spectroscopy in co...
Study of metal-lipopeptide complexes and their self-assembly behavior, micelle ...
Janek, Tomasz; Rodrigues, L. R.; Czyznikowska, ZanetaThe present study aimed to explore the interactions of divalent counterions with biomolecular amphisin using circular dichroism (CD), ultravioletvisible (UVVis) and density functional theory (DFT). The binding mode of interactions between metal-amphisin complexes and bovine serum albumin (BSA) were studied using fluorescence spectroscopy. The results showed that Cu2+ is coordinated by one oxygen atom of the asp...
Physicochemical study of biomolecular interactions between lysosomotropic surfa...
Janek, Tomasz; Czyznikowska, Zaneta; Luczynski, Jacek; Gudiña, Eduardo J.; Rodrigues, L. R.; Galezowska, JoannaThe interactions between two cationic lysosomotropic surfactants (2-dodecanoyloxyethyl)trimethylammonium bromide (DMM-11) and (2-dodecanoyloxypropyl)trimethylammonium bromide (DMPM-11) with bovine serum albumin (BSA) in Hepes buffer (pH = 7.4) were systematically studied by surface tension, fluorescence and circular dichroism (CD) spectroscopy and isothermal titration calorimetry (ITC). Furthermore, the size of...
Structure and mode of action of cyclic lipopeptide pseudofactin II with divalen...
Janek, Tomasz; Rodrigues, L. R.; Gudiña, Eduardo J.; Czyznikowska, Zaneta"Available online 28 June 2016"; The interaction of natural lipopeptide pseudofactin II with a series of doubly charged metal cations was examined by matrixassisted laserdesorption ionizationtime of flight (MALDI-TOF) mass spectrometry and molecular modelling. The molecular modelling for metal-pseudofactin II provides information on the metalpeptide binding sites. Overall, Mg2+, Ca2+ and Zn2+ favor the associat...