2 documents found, page 1 of 1
Promoter methylation of the MGAT3 and BACH2 genes correlates with the compositi...
Klasic, M; Markulin, D; Vojta, A; Samaržija, I; Biruš, I; Dobrinic, P; Ventham, N; Trbojevic-Akmacic, I; Šimurina, M; Štambuk, J; Razdorov, GBackground: Many genome- and epigenome-wide association studies (GWAS and EWAS) and studies of promoter methylation of candidate genes for inflammatory bowel disease (IBD) have demonstrated significant associations between genetic and epigenetic changes and IBD. Independent GWA studies have identified genetic variants in the BACH2, IL6ST, LAMB1, IKZF1, and MGAT3 loci to be associated with both IBD and immunoglo...
Non-colorectal intestinal tract carcinomas in inflammatory bowel disease: resul...
Egan, L; D'Inca, R; Jess, T; Pellino, G; Carbonnel, F; Bokemeyer, B; Harbord, M; Nunes, P; Van der Woude, J; Selvaggi, F; Triantafillidis, JPatients with inflammatory bowel diseases (IBD) have an excess risk of certain gastrointestinal cancers. Much work has focused on colon cancer in IBD patients, but comparatively less is known about other more rare cancers. The European Crohn's and Colitis Organization established a pathogenesis workshop to review what is known about these cancers and formulate proposals for future studies to address the most im...