11 documents found, page 1 of 2
Thickness and immunohistochemistry of LASIK flaps created by different femtosec...
Oliveira,Grazielly Martins Peixoto de; Nosé,Walton; Dagli,Maria Lúcia Zaidan; Cordeiro,Vanessa Vieira; Pereira,Nicolas Cesário; Forseto,Adriana S.ABSTRACT Purpose: The aim of this study was to compare the corneal cell viability and thickness of LASIK flaps created by 3 femtosecond lasers in eye-bank human corneas. Methods: Forty-five eye-bank human sclerocorneal buttons (15 corneas in each group) were examined after the creation of 120 mm-thick laser-assisted keratomileusis (LASIK) flaps with 150kHz iFS IntraLase™ (IL), Z6 Femto LDV™ (LDV), or 200kHz Wa...
Environmental risk factors related to the development of canine non-Hodgkin's l...
Zanini,Danielle Almeida; Kimura,Katia Cristina; Nishiya,Adriana Tomoko; Ubukata,Rodrigo; Leandro,Rafael Magdanelo; Brito,Claudia Prado deThis research aimed to investigate the possible risk factors associated with the development of canine non-Hodgkin's lymphoma. Owners of 83 dogs with non-Hodgkin's lymphoma and of 84 healthy dogs answered an epidemiological questionnaire. Dogs who lived outside of the house and within 100 meters of busy streets or avenues (defined as more than 50 vehicles per minute) had a higher risk for developing the disease...
Sewage sludge does not induce genotoxicity and carcinogenesis
Silva,Paula Regina Pereira; Barbisan,Luis Fernando; Dagli,Maria Lúcia Zaidan; Saldiva,Paulo Hilário NascimentoThrough a series of experiments, the genotoxic/mutagenic and carcinogenic potential of sewage sludge was assessed. Male Wistar rats were randomly assigned to four groups: Group 1 - negative control; Group 2 - liver carcinogenesis initiated by diethylnitrosamine (DEN; 200 mg/kg i.p.); Group 3 and G4- liver carcinogenesis initiated by DEN and fed 10,000 ppm or 50,000 ppm of sewage sludge. The animals were submitt...
Hepatotrophic factors reduce hepatic fibrosis in rats
Cogliati,Bruno; Pereira,Hélder de Moraes; Dagli,Maria Lúcia Zaidan; Parra,Osório Miguel; Silva,José Roberto Machado Cunha daCONTEXT: Hepatic fibrosis occurs in response to several aggressive agents and is a predisposing factor in cirrhosis. Hepatotrophic factors were shown to stimulate liver growth and to restore the histological architecture of the liver. They also cause an improvement in liver function and accelerate the reversion of fibrosis before it progresses to cirrhosis. OBJECTIVE: To test the effects of hepatic fibrosis sol...
Inhibition of ascitic ehrlich tumor cell growth by intraperitoneal injection of...
Vieira,Juliana; Matsuzaki,Patricia; Nagamine,Márcia Kazumi; Haraguchi,Mitsue; Akisue,Gokithi; Gorniak,Silvana Lima; Dagli,Maria Lúcia ZaidanThis study aimed to investigate the effects of the administration of butanolic residue (BR) of Pfaffia paniculata by intraperitoneal route to Ehrlich ascitis tumor bearing mice. Initially, a toxicity study of P. paniculata BR was performed in which doses of 12.5; 25 and 50mg/Kg were administered by intraperitoneal injection for seven days to Swiss mice. The treatment did not show toxicity. Then, Swiss male mice...
Remyelination in experimentally demyelinated connexin 32 KnockOut mice
Ramos,Adriano Tony; Maiorka,Paulo César; Dagli,Maria Lúcia Zaidan; Hosomi,Fernando Yutaka Moniwa; Violin,Kalan Bastos; Latorre,AndréaThe aim of this study was to evaluate the role of connexin 32 (Cx 32) during remyelination of the peripheral nervous system, through a local injection of either 0,1% ethidium bromide solution or saline in the sciatic nerve of Cx 32 knockout mice. Euthanasia was performed ranging from 1, 2, 3, 7, 15, 21 to 30 days after injection. Histochemical, immunohistochemical, immunofluorescence and transmission electron m...
Marcação imunoistoquímica da expressão astrocitária de proteína glial fibrilar ...
Orsini,Heloísa; Bondan,Eduardo Fernandes; Sanchez,Melissa; Lallo,Maria Anete; Maiorka,Paulo César; Dagli,Maria Lúcia Zaidan; Graça,Dominguita LuthersUma vez que muitos dos aspectos envolvidos na patogenia dos processos desmielinizantes do sistema nervoso central (SNC) são ainda pouco esclarecidos e que os astrócitos parecem estar envolvidos na mediação de tais processos, este estudo analisou morfologicamente a participação astrocitária na desmielinização do SNC por meio da marcação imunoistoquímica de duas proteínas dos filamentos intermediários astrocitári...
Marcação imuno-histoquímica da resposta macrofágica e astrocitária no tronco en...
Sanchez,Melissa; Bondan,Eduardo Fernandes; Lallo,Maria Anete; Sinhorini,Idércio Luiz; Dagli,Maria Lúcia Zaidan; Maiorka,Paulo CesarO gliotóxico brometo de etídio (BE) foi utilizado para o estudo da resposta macrofágica e astrocitária sob imunossupressão com ciclofosfamida (CY). Investigou-se a imunorreatividade astrocitária à proteína glial fibrilar ácida (GFAP) e à vimentina (VIM), e a imunorreatividade macrofágica ao ED1 após injeção do BE. Foram utilizados ratos Wistar adultos injetados na cisterna basal com salina a 0,9% (grupo I), BE ...
Canine lacrimal and third eyelid superficial glands macroscopic and morphometr...
Cabral,Vânia Pais; Laus,José Luiz; Dagli,Maria Lúcia Zaidan; Pereira,Gener Tadeu; Talieri,Ivia Carmem; Monteiro,Eduardo Raposo; Mamede,Fabrício VillelaThe lacrimal and third eyelid superficial glands produce the aqueous component of the preocular tear film. In this research, morphologic and morphometric assessments of the parenchyma and stroma of both lacrimal glands of healthy adult mongrel dogs were performed. Both lacrimal and third eyelid glands of fourteen dogs were collected, summing fifty-six samples. The macroscopic and morphometric data were statisti...
Estudo da imunorreatividade astrocitária para GFAP e vimentina no tronco encefá...
Bondan,Eduardo Fernandes; Lallo,Maria Anete; Dagli,Maria Lúcia Zaidan; Sanchez,Melissa; Graça,Dominguita LühersINTRODUÇÃO: O brometo de etídio (BE) é reconhecido como um agente gliotóxico que causa desaparecimento focal astrocitário e oligodendroglial. OBJETIVO: Investigou-se a imunorreatividade astrocitária à proteína glial fibrilar ácida (GFAP) e à vimentina (VIM) após injeção do BE. MÉTODO: Ratos Wistar adultos foram tomados como controles histológicos (grupo H) ou injetados na cisterna basal com BE a 0,1% (grupo E) ...