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Neonatal Escherichia coli K1 meningitis causes learning and memory impairments ...

Vilela, Márcia Carvalho; Barichello, Tatiana; Dagostim, Valdemira S.; Generoso, Jaqueline S.; Simões, Lutiana R.; Dominguini, Diogo; Silvestre, Cintia

Neonatal Escherichia coli meningitis continues to be an important cause of mortality and morbidity in newborns worldwide. The aim of this study was to investigate the cytokines/chemokines, brain-derived neurotrophic factor (BDNF) levels, blood–brain barrier integrity in neonatal rats following E. coli K1 experimental meningitis infection and subsequent behavioural parameters in adulthood. In the hippocampus, in...

Date: 2018   |   Origin: Oasisbr
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