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New and repurposed drugs to treat multidrug- and extensively drug-resistant tub...

Silva, DR; Dalcolmo, M; Tiberi, S; Arbex, MA; Munoz-Torrico, M; Duarte, R; D'Ambrosio, L; Visca, D; Rendon, A; Gaga, M; Zumla, A; Migliori, GB

Multidrug-resistant and extensively drug-resistant tuberculosis (MDR-TB and XDR-TB, respectively) continue to represent a challenge for clinicians and public health authorities. Unfortunately, although there have been encouraging reports of higher success rates, the overall rate of favorable outcomes of M/XDR-TB treatment is only 54%, or much lower when the spectrum of drug resistance is beyond that of XDR-TB. ...


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