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CD20+ T cells in monoclonal B cell lymphocytosis and chronic lymphocytic leukem...

Rodrigues, Cristiana; Laranjeira, Paula; Pinho, A. C. O.; Silva, Isabel; Silva, Sandra; Coucelo, Margarida; Oliveira, Ana Catarina; Simões, Ana Teresa

Introduction: In monoclonal B cell lymphocytosis (MBL) and chronic lymphocytic leukemia (CLL), the expansion of malignant B cells disrupts the normal homeostasis and interactions between B cells and T cells, leading to immune dysregulation. CD20+ T cells are a subpopulation of T cells that appear to be involved in autoimmune diseases and cancer. Methods: Here, we quantified and phenotypically characterized CD20...

Date: 2024   |   Origin: Instituto Politécnico de Coimbra
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