9 documents found, page 1 of 1
Atenção à saúde do idoso na prevenção de doenças cardiovasculares (FF00.2003.AI...
Pedrosa, Carina Cavalcante; Silva, Brenna Pinheiro; Azevedo, Isabella Evelyn Prado de; Menezes, Ramon Róseo Paula Pessoa Bezerra de; Sampaio, Tiago LimaO rápido envelhecimento da população brasileira requer grandes mudanças no modo como as práticas em saúde são realizadas, com ênfase em diagnosticar e tratar corretamente as doenças associadas à terceira idade. A Doença Cardiovascular (DCV) é altamente prevalente, sendo a principal causa de óbito em pacientes com mais de 65 anos. Dessa forma, o diagnóstico e tratamento dessa doença devem ser realizados de forma...
Envolvimento da enzima naphoxidase no efeito nefroprotetor do (-)-α-Bisabolol e...
Sampaio, Tiago LimaAcute Renal Injury (AKI) is associated with high morbidity and mortality, generating public health costs. Ischemia and reperfusion (I/R) are events that frequently lead to AKI due to tissue hypoxia, reactive oxygen species (ROS) production, oxidative stress and programmed cell death by apoptosis. Previously, we have demonstrated the nephroprotective potential of (-)-α-Bisabolol, an unsaturated monocyclic sesqui...
Evaluation of KIM-1 as an early biomarker of snakebite-induced AKI in mice
Dantas, Rodrigo Tavares; Sampaio, Tiago Lima; Lima, Dânya Bandeira; Menezes, Ramon Róseo Paula Pessoa Bezerra de; Canuto, Jader AlmeidaMade available in DSpace on 2018-12-11T17:21:02Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-09-01; Acute kidney injury (AKI) is one of the most important complications of bothropic poisoning and its early identification remains challenging. The nephrotoxicity of Bothrops insularis venom (BinsV) was previously described by our research group. In this study, we continued to evaluate the effect of BinsV...
Involvement of nitric oxide on bothropoides insularis venom biological effects ...
De Menezes, Ramon R.P.P.B.; Mello, Clarissa P.; Lima, Dânya B.; Tessarolo, Louise D.; Sampaio, Tiago Lima; Paes, Lívia C.F.; Alves, Natacha T.Q.Made available in DSpace on 2018-12-11T17:01:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-03-01; Viperidae venom has several local and systemic effects, such as pain, edema, inflammation, kidney failure and coagulopathy. Additionally, bothropic venom and its isolated components directly interfere on cellular metabolism, causing alterations such as cell death and proliferation. Inflammatory cells ar...
Biosafety : microbiological analysis of jackets of u niversity students of heal...
Pinto, Isabela Ribeiro; Sampaio, Tiago Lima; Holanda, Marili a Lima de; Rodrigues Neto, Edilson Martins; Marques, Lidia Audrey Rocha ValadasHealth care students are in permanent contact and h andling with biological agents, and using jackets i n inappropriate environments and can contaminate clot hing, other students, the environment and the popul ation. The present study aimed to verify the contamination rat e of jackets of students investigating the situatio n of biosafety. The collect was held with sterile swab in the tissu es, in an area of app...
Betulinic acid induces cell death by necrosis in Trypanosoma cruzi
Sousa, Paloma Leão; Souza, Racquel Oliveira da Silva; Tessarolo, Louise Donadello; Menezes, Ramon Róseo Paula Pessoa Bezerra de; Sampaio, Tiago LimaChagas ’ disease is a neglected disease caused by the protozoan parasite Trypanosoma cruzi and constitutes a serious health problem worldwide. The treatment is limited, with variable e ffi cacy of benznidazole and ni- furtimox. Betulinic Acid (BA), a triterpene, can be found in medicinal herbs and has a wide variety of biological and pharmacological activities. The objective was to evaluate betulinic acid e ff ...
Efeito nefroprotetor do (-)-α-bisabolol na lesão renal aguda em modelos de isqu...
Sampaio, Tiago LimaIschemia / reperfusion (IR) is a complex phenomenon that contributes to mortality and morbidity and is a predisposing factor for the establishment of acute kidney injury (AKI). Various strategies and resources are used by cells to prevent or decrease the cellular injury caused by oxidative stress. Thus, it emphasizes the importance of studying using substances such as (-)-α-Bisabolol, which has an antioxidant p...
Involvement of nitric oxide on bothropoides insularis venom biological effects ...
Menezes, Ramon R. P. P. B.de; Mello, Clarissa P.; Lima, Dânya B.; Tessarolo, Louise D.; Sampaio, Tiago Lima; Paes, Lívia C. F.Viperidae venom has several local and systemic effects, such as pain, edema, inflammation, kidney failure and coagulopathy. Additionally, bothropic venom and its isolated components directly interfere on cellular metabolism, causing alterations such as cell death and proliferation. Inflammatory cells are particularly involved in pathological envenomation mechanisms due to their capacity of releasing many mediat...
Antimicrobial effect of Dinoponera quadriceps (Hymenoptera: Formicidae) venom a...
Lima, Danya Bandeira; Torres, Alba Fabíola Costa; Mello, Clarissa Perdigão; Menezes, Ramon Róseo Paula Pessoa Bezerra; Sampaio, Tiago LimaAims: Dinoponera quadriceps venom (DqV) was examined to evaluate the antibacterial activity and its bactericidal action mechanism against Staphylococcus aureus. Methods and Results: DqV was tested against a standard strain of methicillinsensitive Staphylococcus aureus (MSSA), Staph. aureus ATCC 6538P and two standard strains of methicillin-resistant Staphylococcus aureus (MRSA), Staph. aureus ATCC 33591 and Sta...