14 documents found, page 1 of 2
Evaluation of diagnosis and treatment practices of Brazilian neurologists among...
Marin,Cássia Elisa; Callegaro,Dagoberto; Lana-Peixoto,Marco Aurélio; Fernández,Oscar; Gomes Neto,Antonio Pereira; Vasconcelos,Claudia Cristina FerreiraABSTRACT Background: Recent changes to the diagnostic criteria for multiple sclerosis (MS) and new medications have had a major impact on the way in which specialists manage the disease. Objective: To investigate factors considered by Brazilian neurologists in managing MS, and to identify how these contribute to diagnosis and treatment. Methods: Potential participants were selected by a steering committee (MS e...
Recommendations by the Scientific Department of Neuroimmunology of the Brazilia...
Becker,Jefferson; Ferreira,Lis Campos; Damasceno,Alfredo; Bichuetti,Denis Bernardi; Christo,Paulo Pereira; Callegaro,DagobertoABSTRACT The Scientific Department of Neuroimmunology of the Brazilian Academy of Neurology (DCNI/ABN) and Brazilian Committee for Treatment and Research in Multiple Sclerosis and Neuroimmunological Diseases (BCTRIMS) provide recommendations in this document for vaccination of the population with demyelinating diseases of the central nervous system (CNS) against infections in general and against the severe acut...
Normative values of the Brief Repeatable Battery of Neuropsychological Tests in...
Damasceno,Alfredo; Amaral,Juliana Machado Santiago dos Santos; Barreira,Amilton Antunes; Becker,Jefferson; Callegaro,Dagoberto; Campanholo,Kenia RepisoABSTRACT Objective Cognitive dysfunction is common in multiple sclerosis. The Brief Repeatable Battery of Neuropsychological Tests (BRB–N) was developed to assess cognitive functions most–frequently impaired in multiple sclerosis. However, normative values are lacking in Brazil. Therefore, we aimed to provide continuous and discrete normative values for the BRB–N in a Brazilian population sample. Methods We rec...
Brazilian Consensus for the Treatment of Multiple Sclerosis: Brazilian Academy ...
Marques,Vanessa Daccach; Passos,Giordani Rodrigues dos; Mendes,Maria Fernanda; Callegaro,Dagoberto; Lana-Peixoto,Marco AurélioABSTRACT The expanding therapeutic arsenal in multiple sclerosis (MS) has allowed for more effective and personalized treatment, but the choice and management of disease-modifying therapies (DMTs) is becoming increasingly complex. In this context, experts from the Brazilian Committee on Treatment and Research in Multiple Sclerosis and the Neuroimmunology Scientific Department of the Brazilian Academy of Neurolo...
LOW-LOAD RESISTANCE EXERCISE IMPROVES COGNITIVE FUNCTION IN OLDER ADULTS
Sardeli,Amanda Veiga; Ferreira,Marina Lívia Venturini; Santos,Lucas do Carmo; Rodrigues,Marília de Souza; Damasceno,Alfredo; Cavaglieri,Cláudia ReginaABSTRACT Introduction: Resistance exercise (RE) training is widely recommended for increasing muscle strength and mass in older adults. RE is also a potential stimulus to improve cognitive functions (CF), but the best protocol for this purpose is unknown. Objective: To compare the effects of different RE protocols on CF in the same group of individuals. Methods: Twenty-four older adults were randomized (cross o...
Safety of switching from natalizumab straight into fingolimod in a group of JCV...
Fragoso,Yara Dadalti; Alves-Leon,Soniza Vieira; Becker,Jefferson; Brooks,Joseph Bruno Bidin; Correa,Eber Castro; Damasceno,Alfredo; Gama,Paulo Diniz daABSTRACT Objective To assess safety of the switch between natalizumab and fingolimod without a washout period. Methods Prospective data on 25 JCV positive patients who underwent this medication switch were collected and analyzed. Results After a median period of nine months from the medication switch, there were no safety issues to report. The patients had good disease control and no adverse events were reporte...
Cortical correlates of affective syndrome in dementia due to Alzheimer’s disease
Hayata,Thaís T.; Bergo,Felipe P. G.; Rezende,Thiago J.; Damasceno,Alfredo; Damasceno,Benito P.; Cendes,Fernando; Stella,Florindo; Balthazar,Marcio L. F.Neuropsychiatric symptoms in Alzheimer’s disease (AD) are prevalent, however their relationship with patterns of cortical atrophy is not fully known. Objectives To compare cortical atrophy’s patterns between AD patients and healthy controls; to verify correlations between neuropsychiatric syndromes and cortical atrophy. Method 33 AD patients were examined by Neuropsychiatric Inventory (NPI). Patients and 29 con...
The real-life experience with cardiovascular complications in the first dose of...
Fragoso,Yara Dadalti; Arruda,Christian Cardoso; Arruda,Walter Oleschko; Brooks,Joseph Bruno Bidin; Damasceno,AlfredoFingolimod is a new and efficient treatment for multiple sclerosis (MS). The drug administration requires special attention to the first dose, since cardiovascular adverse events can be observed during the initial six hours of fingolimod ingestion. The present study consisted of a review of cardiovascular data on 180 patients with MS receiving the first dose of fingolimod. The rate of bradycardia in these patie...
Visual pathway abnormalities were found in most multiple sclerosis patients des...
Castro,Stella Maris Costa; Damasceno,Alfredo; Damasceno,Benito Pereira; Vasconcellos,Jose Paulo de; Reis,Fabiano; Iyeyasu,Josie NaomiObjectiveIt was to investigate visual field (VF) abnormalities in a group of multiple sclerosis (MS) patients in the remission phase and the presence of magnetic resonance imaging (MRI) lesions in the optic radiations.MethodsVF was assessed in 60 participants (age range 20-51 years): 35 relapsing-remitting MS patients [20 optic neuritis (+), 15 optic neuritis (-)] and 25 controls. MRI (3-Tesla) was obtained in ...
Multiple sclerosis in South America: month of birth in different latitudes does...
Fragoso,Yara Dadalti; Adoni,Tarso; Almeida,Sandra Maria Garcia de; Alves-Leon,Soniza Vieira; Arruda,Walter Oleschko; Barbagelata-Aguero,FiorellaObjective To assess whether the month of birth in different latitudes of South America might influence the presence or severity of multiple sclerosis (MS) later in life. Methods Neurologists in four South American countries working at MS units collected data on their patients' month of birth, gender, age, and disease progression. Results Analysis of data from 1207 MS patients and 1207 control subjects did not s...