12 documents found, page 1 of 2

Cortical correlates of affective syndrome in dementia due to Alzheimer’s disease

Neuropsychiatric symptoms in Alzheimer’s disease (AD) are prevalent, however their relationship with patterns of cortical atrophy is not fully known. Objectives To compare cortical atrophy’s patterns between AD patients and healthy controls; to verify correlations between neuropsychiatric syndromes and cortical atrophy. Method 33 AD patients were examined by Neuropsychiatric Inventory (NPI). Patients and 29 con...

Relationship between cortical microinfarcts and cognitive impairment in Alzheim...

ABSTRACT Cerebrovascular disease and AD pathology co-exist in most dementia cases, and microinfarcts (MIs), particularly if cortical and multiple, play an additive and independent role in AD cognitive impairment. The main cause of cortical MIs is chronic cerebral hypoperfusion but occlusive vascular diseases, embolism and blood-brain barrier disruptions, isolated or combined, may also play a role. The precise m...

Short-term prognosis for speech and language in first stroke patients

OBJECTIVE: To evaluate the factors that can influence evolution of communication after a first stroke. METHOD: Thirty-seven adult patients were evaluated for speech and language within 72 hours after a single first-ever ischemic brain injury and later on. Patients who were comatose, with decompensated systemic diseases, or history of chronic alcoholism or illicit drug use were not included. Brain CT and/or 2T-M...

Bickerstaff 's encephalitis, Guillain-Barré syndrome and idiopathic intracrania...

Lexical semantic memory in amnestic mild cognitive impairment and mild Alzheime...

OBJECTIVE: To study lexical semantic memory in patients with amnestic mild cognitive impairment (aMCI), mild Alzheimer's disease (AD) and normal controls. METHOD: Fifteen mild AD, 15 aMCI, and 15 normal control subjects were included. Diagnosis of AD was based on DSM-IV and NINCDS-ADRDA criteria, and that of aMCI, on the criteria of the International Working Group on Mild Cognitive Impairment, using CDR 0.5 for...

Theory of mind and the frontal lobes

BACKGROUND: Theory of mind (ToM) is the ability to attribute mental states to other individuals. Its cerebral organization is not enough established, even though the literature suggests the relevant role of the frontal lobes. OBEJECTIVE: To evaluate frontal lobe patients and controls in ToM tests. METHOD:We studied 20 patients with lesions limited to the frontal lobes (as shown by CT or MRI), and 10 normal cont...

Validation of the Brazilian version of mini-test CASI-S

OBJECTIVE: To determine CASI-S accuracy in the diagnosis of dementia. METHOD: The Cognitive Abilities Screening Instrument - Short Form (CASI-S) was applied in 43 Alzheimer's disease (AD) patients and 74 normal controls. AD diagnosis was based on DSM-IV, NINCDS-ADRDA, and CAMDEX. CASI-S includes: registration, temporal orientation, verbal fluency (4-legged animals in 30s), and recall (3 words). Its maximum scor...

Primitive reflexes and cognitive function

BACKGROUND: Data on the prevalence of primitive reflexes (PR) in adulthood, their pathological significance and relationship to age and cognition are controversial. OBJECTIVE: To study the relationship between PR and cognition in 30 patients with probable Alzheimer's disease (AD) and 154 control subjects. METHOD: Diagnosis of probable AD was based on DSM-IV, NINCDS-ADRDA, and CAMDEX criteria. Primitive reflexes...

Whipple's disease with neurological manifestions: case report

Whipple's disease (WD) is an uncommon multisystem condition caused by the bacillus Tropheryma whipplei. Central nervous system involvement is a classical feature of the disease observed in 20 to 40% of the patients. We report the case of a 62 yeards old man with WD that developed neurological manifestations during its course, and discuss the most usual signs and symptoms focusing on recent diagnostic criteria a...

Demência na população de pacientes do Hospital das Clínicas da Unicamp

OBJETIVO: Descrever subtipos de demência em pacientes atendidos no HC-UNICAMP. METODO: No período 1989-1998, foram admitidos 261 pacientes com demência (89,7% estudados retrospectivamente, e 10,3% prospectivamente); idade 63,5 anos (±13,2) e educação 3,6 anos (±3,9; 25% analfabetos). O diagnóstico de demência e seus subtipos baseou-se no DSM-IV, CAMDEX, NINCDS-ADRDA, NINDS-AIREN/ADDTC, Lund-Manchester, tap-test...