50 documents found, page 1 of 5
Resveratrol-loaded polydimethylsiloxane-silica hybrid materials: synthesis, cha...
Viegas, Sofia; Marinheiro, Diogo; Bastos, Verónica; Daniel-da-Silva, Ana L.; Vieira, Ricardo; Oliveira, Helena; Almeida, José CarlosIn this work, hybrid materials within the polydimethylsiloxane-silica (PDMS-SiO2) system, synthesized via the sol-gel method, were developed and characterized for their potential to incorporate and release the bioactive compound resveratrol (RES). RES was incorporated into the materials with a high loading efficiency (>75%) using the rotary evaporator technique. This incorporation induced the amorphization of R...
Magneto-plasmonic bionanocomposites for on-site SERS detection of water contami...
Soares, Sofia F.; Silva, Nuno M. A. S.; Brenheiro, João; Fateixa, Sara; Daniel-da-Silva, Ana L.; Trindade, TitoMagneto-plasmonic nanosystems have emerged as important multifunctional structures for several sensing applications, including on-site water quality monitoring. In this scenario, these nanosystems can integrate magnetic assisted separation procedures associated with optical detection of water contaminants, by exploring the surface-enhanced Raman scattering effect (SERS). Among the several modalities proposed fo...
Integrated magneto-plasmonic nanostructures-based immunoassay for galectin-3 de...
Fateixa, Sara; Martins, Ana L. F.; Colaço, Beatriz; António, Maria; Daniel-da-Silva, Ana L.Cardiovascular diseases remain a leading cause of global mortality, highlighting the need for accurate diagnostic tools and the detection of specific cardiac biomarkers. Surface-enhanced Raman scattering (SERS) spectroscopy has proved to be a promising alternative diagnostic tool to detect relevant biomarkers compared to traditional methods. To our knowledge, SERS methodology has never been used to detect galec...
A comprehensive ecotoxicity study of molybdenum disulfide nanosheets versus bul...
Santos, Joana; Barreto, Ângela; Fernandes, Cristiana; Silva, Ana Rita R.; Cardoso, Diogo N.; Pinto, Edgar; Daniel-da-Silva, Ana L.; Maria, Vera L.The increasing use of molybdenum disulfide (MoS2) nanoparticles (NPs) raises concerns regarding their accumulation in soil ecosystems, with limited studies on their impact on soil organisms. Study aim: To unravel the effects of MoS2 nanosheets (two-dimensional (2D) MoS2 NPs) and bulk MoS2 (156, 313, 625, 1250, 2500 mg/kg) on Enchytraeus crypticus and Folsomia candida. The organisms’ survival and avoidance behav...
Gold nanoparticle probes for colorimetric detection of plasma galectin-3: a sim...
António, Maria; Lima, Tânia; Ferreira, Rita; Fardilha, Margarida; Bastos, José Mesquita; Vitorino, Rui; Daniel-da-Silva, Ana L.Galectin-3 (Gal-3) is a carbohydrate-binding protein associated with the development and progress of heart failure. Here, we report the first colorimetric and low-cost approach for detecting and quantifying Gal-3 using gold nanoparticles (AuNPs) bioconjugated with Gal-3 antibody. The interaction of Gal-3 with the resulting nanoprobes led to a linear response of the absorbance ratio A750nm/A526nm to Gal-3 concen...
Drug Delivery Systems and Flavonoids: Current Knowledge in Melanoma Treatment a...
Cunha, Catarina; Daniel-da-Silva, Ana L.; Oliveira, HelenaMelanoma is an aggressive form of skin cancer with a high prevalence in the population. An early diagnosis is crucial to cure this disease. Still, when this is not possible, combining potent pharmacological agents and effective drug delivery systems is essential to achieve optimal treatment and improve patients' quality of life. Nanotechnology application in biomedical sciences to encapsulate anticancer drugs, ...
MoS2 and MoS2 Nanocomposites for Adsorption and Photodegradation of Water Pollu...
Amaral, Leonardo O.; Daniel-da-Silva, Ana L.The need for fresh and conveniently treated water has become a major concern in recent years. Molybdenum disulfide (MoS2) nanomaterials are attracting attention in various fields, such as energy, hydrogen production, and water decontamination. This review provides an overview of the recent developments in MoS2-based nanomaterials for water treatment via adsorption and photodegradation. Primary attention is give...
Towards efficient ciprofloxacin adsorption using magnetic hybrid nanoparticles ...
Soares, Sofia F.; Nogueira, João; Trindade, Tito; Daniel-da-Silva, Ana L.The efficient removal of the antibiotic ciprofloxacin (CIP) from aqueous samples using magnetic nanosorbents prepared using three sulfated polysaccharides, κ-, ι- and λ-carrageenan and an alkoxysilane agent containing a reactive epoxide ring is described. The prepared nanosorbents were characterized in detail using FTIR spectroscopy, solid-state 29Si and 13C NMR spectroscopy and elemental microanalysis. The syn...
Colloidal nanomaterials for water quality improvement and monitoring
Estrada, Ana C.; Daniel-da-Silva, Ana L.; Leal, Cátia; Monteiro, Cátia; Lopes, Cláudia B.; Nogueira, Helena I. S.; Lopes, Isabel; Martins, Maria J.Water is the most important resource for all kind forms of live. It is a vital resource distributed unequally across different regions of the globe, with populations already living with water scarcity, a situation that is spreading due to the impact of climate change. The reversal of this tendency and the mitigation of its disastrous consequences is a global challenge posed to Humanity, with the scientific comm...
Chemical strategies for dendritic magneto-plasmonic nanostructures applied to s...
Fernandes, Tiago; Nogueira, Helena I. S.; Amorim, Carlos O.; Amaral, João S.; Daniel-da-Silva, Ana L.; Trindade, TitoChemical analyses in the field using surface-enhanced Raman scattering (SERS) protocols are expected to be part of several analytical procedures applied to water quality monitoring. To date, these endeavors have been supported by developments in SERS substrate nanofabrication, instrumentation portability, and the internet of things. Here, we report distinct chemical strategies for preparing magneto-plasmonic (F...