47 documents found, page 1 of 5
A comprehensive ecotoxicity study of molybdenum disulfide nanosheets versus bul...
Santos, Joana; Barreto, Ângela; Fernandes, Cristiana; Silva, Ana Rita R.; Cardoso, Diogo N.; Pinto, Edgar; Daniel-da-Silva, Ana L.; Maria, Vera L.The increasing use of molybdenum disulfide (MoS2) nanoparticles (NPs) raises concerns regarding their accumulation in soil ecosystems, with limited studies on their impact on soil organisms. Study aim: To unravel the effects of MoS2 nanosheets (two-dimensional (2D) MoS2 NPs) and bulk MoS2 (156, 313, 625, 1250, 2500 mg/kg) on Enchytraeus crypticus and Folsomia candida. The organisms’ survival and avoidance behav...
Gold nanoparticle probes for colorimetric detection of plasma galectin-3: a sim...
António, Maria; Lima, Tânia; Ferreira, Rita; Fardilha, Margarida; Bastos, José Mesquita; Vitorino, Rui; Daniel-da-Silva, Ana L.Galectin-3 (Gal-3) is a carbohydrate-binding protein associated with the development and progress of heart failure. Here, we report the first colorimetric and low-cost approach for detecting and quantifying Gal-3 using gold nanoparticles (AuNPs) bioconjugated with Gal-3 antibody. The interaction of Gal-3 with the resulting nanoprobes led to a linear response of the absorbance ratio A750nm/A526nm to Gal-3 concen...
Towards efficient ciprofloxacin adsorption using magnetic hybrid nanoparticles ...
Soares, Sofia F.; Nogueira, João; Trindade, Tito; Daniel-da-Silva, Ana L.The efficient removal of the antibiotic ciprofloxacin (CIP) from aqueous samples using magnetic nanosorbents prepared using three sulfated polysaccharides, κ-, ι- and λ-carrageenan and an alkoxysilane agent containing a reactive epoxide ring is described. The prepared nanosorbents were characterized in detail using FTIR spectroscopy, solid-state 29Si and 13C NMR spectroscopy and elemental microanalysis. The syn...
Colloidal nanomaterials for water quality improvement and monitoring
Estrada, Ana C.; Daniel-da-Silva, Ana L.; Leal, Cátia; Monteiro, Cátia; Lopes, Cláudia B.; Nogueira, Helena I. S.; Lopes, Isabel; Martins, Maria J.Water is the most important resource for all kind forms of live. It is a vital resource distributed unequally across different regions of the globe, with populations already living with water scarcity, a situation that is spreading due to the impact of climate change. The reversal of this tendency and the mitigation of its disastrous consequences is a global challenge posed to Humanity, with the scientific comm...
Chemical strategies for dendritic magneto-plasmonic nanostructures applied to s...
Fernandes, Tiago; Nogueira, Helena I. S.; Amorim, Carlos O.; Amaral, João S.; Daniel-da-Silva, Ana L.; Trindade, TitoChemical analyses in the field using surface-enhanced Raman scattering (SERS) protocols are expected to be part of several analytical procedures applied to water quality monitoring. To date, these endeavors have been supported by developments in SERS substrate nanofabrication, instrumentation portability, and the internet of things. Here, we report distinct chemical strategies for preparing magneto-plasmonic (F...
Drug Delivery Systems and Flavonoids: Current Knowledge in Melanoma Treatment a...
Cunha, Catarina; Daniel-da-Silva, Ana L.; Oliveira, HelenaMelanoma is an aggressive form of skin cancer with a high prevalence in the population. An early diagnosis is crucial to cure this disease. Still, when this is not possible, combining potent pharmacological agents and effective drug delivery systems is essential to achieve optimal treatment and improve patients' quality of life. Nanotechnology application in biomedical sciences to encapsulate anticancer drugs, ...
MoS2 and MoS2 Nanocomposites for Adsorption and Photodegradation of Water Pollu...
Amaral, Leonardo O.; Daniel-da-Silva, Ana L.The need for fresh and conveniently treated water has become a major concern in recent years. Molybdenum disulfide (MoS2) nanomaterials are attracting attention in various fields, such as energy, hydrogen production, and water decontamination. This review provides an overview of the recent developments in MoS2-based nanomaterials for water treatment via adsorption and photodegradation. Primary attention is give...
Gold nanoparticles-based assays for biodetection in urine
António, Maria; Vitorino, Rui; Daniel-da-Silva, Ana L.Urine is a biofluid easy to collect through a non-invasive technique that allows collecting a large volume of sample. The use of urine for disease diagnosis is not yet well explored. However, it has gained attention over the last three years. It has been applied in the diagnosis of several illnesses such as kidney disease, bladder cancer, prostate cancer and cardiovascular diseases. In the last decade, gold nan...
A versatile synthetic route towards gelatin-silica hybrids and magnetic composi...
Soares, Sofia F.; Fateixa, Sara; Trindade, Tito; Daniel-da-Silva, Ana L.We report a versatile synthetic route for the preparation of nearly monodispersed spherical gelatin-silica hybrid nanoparticles. These hybrids have been synthesized by means of a non-emulsion sol–gel method involving the base-catalyzed hydrolysis and condensation of gelatin modified with different functional coupling agents. The method is effective for preparing hybrids of both gelatin type A and B, and the alk...
Colloidal dendritic nanostructures of gold and silver for SERS analysis of wate...
Fernandes, Tiago; Fateixa, Sara; Ferro, Marta; Nogueira, Helena I. S.; Daniel-da-Silva, Ana L.; Trindade, TitoSurface-Enhanced Raman Scattering (SERS) using colloidal metal (Ag, Au) nanoparticles has been regarded as a powerful method for detecting organic pollutants at vestigial levels. Although less investi- gated, the controlled synthesis of binary nanostructures comprising two metals provides an alternative route to SERS platforms with tuned surface plasmon resonances. Here, we demonstrate that the use of dendrimer...