4 documents found, page 1 of 1
Synthesis and antimicrobial activity of a new class of azoimidazoles
Dantas, D.; Ribeiro, A.I.; Rodrigues, R.; Carvalho, L.F.; Pinto, E.; Cerqueira, Fátima; Geraldo, D.; Zile, A.; Dias, A.
Animals in biomedical research : towards a more compassionate approach
Reis, J.; Oliveira, T.; Faísca, P.; Dantas, D.; Silva, S.; Frazão, O.The development of novel biosensors and other medical devices often implies extensive animal testing before the final phases of product development are reached. Most products do not reach the market. On the other hand, natural disease in companion animals often mirrors disease processes in humans, being a more accurate representation of the complexity of disease processes than laboratory animals. These are poor...
Novel halochromic and antimicrobial azopyrimidine dyes: synthesis, colorimetric...
Dantas, D.; Ribeiro, A.I.; Carvalho, L.F.; Pinto, E.; Cerqueira, Fátima; Zile, A.; Dias, A.
5-Aminoimidazol-4-carboxamidrazones as potential antifungals: New advances to t...
Carvalho, Filipe; Dantas, D.; Pinto, Eugénia; Cerqueira, Fátima; Dias, AliceChemical assays demonstrated that 5-aminoimidazole-4-carboxamidrazones are very susceptible to oxidation, and it was possible to identify reactive oxygen species during the oxidation process. The presence of acids inhibited oxidation of the compounds, since protonated form is much more stable and resistant to oxidation. Addition of antioxidants was also evaluated and, although some of the antioxidants tested we...