4 documents found, page 1 of 1
Electrochemical characterization of imidazole-based carboxamidrazones in aqueou...
Rodrigues, Rui; Dantas, Daniela; Carvalho, Filipe; Ribeiro, Ana; Zille, Andrea; Silva, Renata; Remião, Fernando; Dias, Alice; Pinto, Eugénia
Mechanism and structure-activity relationship of the antimicrobial imidazole-ba...
Dantas, Daniela; Rodrigues, Rui; Carvalho, Filipe; Ribeiro, Ana; Zille, Andrea; Silva, Renata; Remião, Fernando; Geraldo, Dulce; Pinto, Eugénia
Mechanism of antifungal activity by 5-aminoimidazole-4-carbohydrazonamide deriv...
Cerqueira, Fátima; Maia, Marta; Gabriel, Carla; Medeiros, R.; Cravo, Sara; Ribeiro, Ana Isabel; Dantas, Daniela; Dias, Alice Maria; Saraiva, LucíliaSystemic mycoses are one major cause of morbidity/mortality among immunocompromised/debilitated individuals. Studying the mechanism of action is a strategy to develop safer/potent antifungals, warning resistance emergence. The major goal of this study was to elucidate the mechanism of action of three (Z)-5-amino-N’-aryl-1-methyl-1H-imidazole-4-carbohydrazonamides (2h, 2k, 2l) that had previously demonstrated st...
Mechanism of Antifungal Activity by 5-Aminoimidazole-4-Carbohydrazonamide Deriv...
Cerqueira, Fátima; Maia, Marta; Gabriel, Carla; Medeiros, Rui; Cravo, Sara; Ribeiro, Ana Isabel; Dantas, Daniela; Dias, Alice Maria; Saraiva, LucíliaSystemic mycoses are one major cause of morbidity/mortality among immunocompromised/debilitated individuals. Studying the mechanism of action is a strategy to develop safer/potent antifungals, warning resistance emergence. The major goal of this study was to elucidate the mechanism of action of three (<i>Z</i>)-5-amino-<i>N</i>’-aryl-1-methyl-1<i>H</i>-imidazole-4-carbohydrazonamides (2h, 2k, 2l) that had previ...