13 documents found, page 1 of 2

Synergistic antimicrobial activity of silver nanoparticles with an emergent cla...

he combination of two or more agents capable of acting in synergy has been reported as a valuable tool to fight against pathogens. Silver nanoparticles (AgNPs) present a strong antimicrobial action, although their cytotoxicity for healthy cells at active concentrations is a major concern. Azoimidazole moieties exhibit interesting bioactivities, including antimicrobial activity. In this work, a class of recently...

Red-shifted and pH-responsive imidazole-based Azo Dyes with potent antimicrobia...

A novel route is described to obtain 2 aminoimidazole azo dyes with unique substituents pattern in the heteroaryl unit that provides halochromic properties, exhibiting vibrant colours that change from magenta to deep blue. Potent antimicrobial properties against infectious yeasts were demonstrated. No cytotoxicity was detected for concentrations lower than 16 μg·mL-1

CConjugating azoimidazoles and gold nanoparticles for a synergistic antimicrobi...

Antifungal activity of a new derivative of 5-aminoimidazole-4-carbohydrazonamide

[Excerpt] Fungal infections, as recognized by the World Health Organization (WHO), are among the most worrying challenges for the medical community due to their high incidence, recurrence, and the emergence of resistance to the few available drugs and therapies. The discovery of new molecules with antifungal activity, exhibiting new mechanisms of action and less side effects, thus represents an important step f...

Synergistic antibacterial activity of imidazole-based azo dyes with polyvinylpy...

The high demand for novel antimicrobial textiles by the medical, healthcare, hygiene, sportswear, personal protective equipment, and filtration sectors promoted the growth of functional textiles. However, the efficacy of antimicrobial agents against different pathogens is a considerable challenge due to the distinctive mechanisms of action and resistance. The development of novel synergistic antimicrobial dyes ...

Electrochemical characterization of imidazole-based carboxamidrazones in aqueou...

The search for new antibiotics is an emergent topic in the scientific community due to the appearance of pathogenic organisms multiresistant to the available drugs and therapy [1]. The worrying increase in infections caused by pathogenic fungi in immunosuppressed patients prompted the search for new antifungal agents with new mechanisms of action and less side effects [2]. The imidazole ring is a crucial scaffo...

Synergistic activity of a novel class of azoimidazole dyes with polyvinylpyrrol...

The high demand for novel antimicrobial textiles by the medical, health care, hygiene, sportswear, personal protective equipment, and filtration sectors promoted the growth of functional textiles. However, the efficacy of antimicrobial agents against different pathogens is a considerable challenge due to the distinctive mechanisms of action and resistance. The development of novel synergistic antimicrobial agen...

Halochromic properties of a 5-aminoimidazole-4-carboxamidrazone and its applica...

The application of stimuli-responsive molecules in textiles is an important field due to its potential in various areas of flexible sensing technology. In particular, pH plays an important role in nature, humans, and several processes. The pH of body fluids is one of the best indicators of disturbed health conditions. Thus, the development of textiles with halochromic properties has been increasingly attractive...

Halochromic properties of a 5-aminoimidazole-4-carboxamidrazone and its applica...

Mechanism and structure-activity relationship of the antimicrobial imidazole-ba...

The emergence of infectious diseases caused by new pathogens or multidrug-resistant microorganisms has been a global health threat over the last decades. These infections are among the most severe healthcare problems and have been associated with several deaths and heavy economic burdens per year. The interest in the search for new antifungal agents is also increasing in the scientific community due to the appe...