2 documents found, page 1 of 1
Bonding antimicrobial rhamnolipids onto medical grade PDMS: A strategy to overc...
Dardouri, Maïssa; Aljnadi, Israa M.; Deuermeier, Jonas; Santos, Catarina; Costa, Fabiola; Martin, Victor; Fernandes, Maria H.; Gonçalves, LídiaIn clinic there is a demand to solve the drawback of medical devices multispecies related infections. Consequently, different biomaterial surfaces, such as vascular catheters, urgently need improvement regarding their antifouling/antimicrobial properties. In this work, we covalently functionalized medical grade polydimethylsiloxane (PDMS) with antimicrobial rhamnolipids to investigate the biomaterial surface ac...
Fighting S. aureus catheter-related infections with sophorolipids: Electing an ...
Mendes, Rita M.; Francisco, Ana Paula; Carvalho, Filomena A.; Dardouri, Maïssa; Costa, Bruna; Bettencourt, Ana; Costa, Judite; Gonçalves, LídiaStaphylococcus aureus medical devices related-infections, such as blood stream catheter are of major concern. Their prevention is compulsory and strategies, not prone to the development of resistance, to prevent S. aureus biofilms on catheter surfaces (e.g. silicone) are needed. In this work two different approaches using sophorolipids were studied to prevent S. aureus biofilm formation on medical grade silicon...