2 documents found, page 1 of 1
Prospective Observational Study on acute Appendicitis Worldwide (POSAW)
Sartelli, M; Baiocchi, GL; Di Saverio, S; Ferrara, F; Labricciosa, FM; Ansaloni, L; Coccolini, F; Vijayan, D; Abbas, A; Abongwa, HK; Agboola, JBACKGROUND: Acute appendicitis (AA) is the most common surgical disease, and appendectomy is the treatment of choice in the majority of cases. A correct diagnosis is key for decreasing the negative appendectomy rate. The management can become difficult in case of complicated appendicitis. The aim of this study is to describe the worldwide clinical and diagnostic work-up and management of AA in surgical departme...
The transcriptomic landscape of gastric cancer: Insights into epstein-barr viru...
Gullo, I; Carvalho, J; Martins, D; Lemos, D; Monteiro, AR; Ferreira, M; Das, K; Tan, P; Oliveira, C; Carneiro, F; Oliveira, PBackground: Epstein-Barr Virus (EBV) positive and microsatellite unstable (MSI-high) gastric cancer (GC) are molecular subgroups with distinctive molecular profiles. We explored the transcriptomic differences between EBV+ and MSI-high GCs, and the expression of current GC immunotherapy targets such as PD-1, PD-L1, CTLA4 and Dies1/VISTA. Methods: Using Nanostring Technology and comparative bioinformatics, we ana...