2 documents found, page 1 of 1
Patient profiling in heart failure for tailoring medical therapy: a consensus d...
Rosano, Giuseppe M. C.; Moura, Brenda; Metra, Marco; Böhm, Michael; Bauersachs, Johann; Ben Gal, Tuvia; Adamopoulos, Stamatis; Abdelhamid, MagdyDespite guideline recommendations and available evidence, implementation of treatment in heart failure (HF) is poor. The majority of patients are not prescribed drugs at target doses that have been proven to positively impact morbidity and mortality. Among others, tolerability issues related to low blood pressure, heart rate, impaired renal function or hyperkalaemia are responsible. Chronic kidney disease plays...
Levosimendan efficacy and safety : 20 Years of SIMDAX in clinical use
Papp, Zoltán; Agostoni, Piergiuseppe; Alvarez, Julian; Bettex, Dominique; Bouchez, Stefan; Brito, Dulce; Cˇerný, Vladimir; Comin-Colet, JosepLevosimendan was first approved for clinical use in 2000, when authorization was granted by Swedish regulatory authorities for the hemodynamic stabilization of patients with acutely decompensated chronic heart failure (HF). In the ensuing 20 years, this distinctive inodilator, which enhances cardiac contractility through calcium sensitization and promotes vasodilatation through the opening of adenosine triphosp...