5 documents found, page 1 of 1
Paving Luteolin Therapeutic Potentialities and Agro-Food-Pharma Applications: E...
Taheri, Y; Sharifi-Rad, J; Antika, G; Yilmaz, YB; Tumer, TB; Abuhamdah, S; Chandra, S; Saklani, S; Kiliç, CS; Sestito, S; Dastan, SD; Kumar, MLuteolin is a naturally occurring secondary metabolite belonging to the class of flavones. As many other natural flavonoids, it is often found in combination with glycosides in many fruits, vegetables, and plants, contributing to their biological and pharmacological value. Many preclinical studies report that luteolin present excellent antioxidant, anticancer, antimicrobial, neuroprotective, cardioprotective, a...
Paclitaxel: Application in Modern Oncology and Nanomedicine-Based Cancer Therapy
Sharifi-Rad, J; Quispe, C; Patra, JK; Singh, YD; Panda, MK; Das, G; Adetunji, CO; Michael, OS; Sytar, O; Polito, L; Živkovic, J; Martins, NPaclitaxel is a broad-spectrum anticancer compound, which was derived mainly from a medicinal plant, in particular, from the bark of the yew tree Taxus brevifolia Nutt. It is a representative of a class of diterpene taxanes, which are nowadays used as the most common chemotherapeutic agent against many forms of cancer. It possesses scientifically proven anticancer activity against, e.g., ovarian, lung, and brea...
Production, Transmission, Pathogenesis, and Control of Dengue Virus: A Literatu...
Islam, MT; Quispe, C; Herrera-Bravo, J; Sarkar, C; Sharma, R; Garg, N; Fredes, LI; Martorell, M; Alshehri, MM; Sharifi-Rad, J; Dastan, SD; Calina, DDengue remains one of the most serious and widespread mosquito-borne viral infections in human beings, with serious health problems or even death. About 50 to 100 million people are newly infected annually, with almost 2.5 billion people living at risk and resulting in 20,000 deaths. Dengue virus infection is especially transmitted through bites of Aedes mosquitos, hugely spread in tropical and subtropical envi...
Lasia spinosa Chemical Composition and Therapeutic Potential: A Literature-Base...
Hossain, R; Quispe, C; Herrera-Bravo, J; Islam, MS; Sarkar, C; Islam, MT; Martorell, M; Martins, N; Al-Harrasi, A; Al-Rawahi, A; Sharifi-Rad, JLasia spinosa (L.) is used ethnobotanically for the treatment of various diseases, including rheumatoid arthritis, inflammation of the lungs, bleeding cough, hemorrhoids, intestinal diseases, stomach pain, and uterine cancer. This review is aimed at summarizing phytochemistry and pharmacological data with their molecular mechanisms of action. A search was performed in databases such as PubMed, Science Direct, a...
Therapeutic Potential of Isoflavones with an Emphasis on Daidzein
Alshehri, MM; Sharifi-Rad, J; Herrera-Bravo, J; Jara, EL; Salazar, LA; Kregiel, D; Uprety, Y; Akram, M; Iqbal, M; Martorell, M; Torrens-Mas, M; Pons, DGDaidzein is a phytoestrogen isoflavone found in soybeans and other legumes. The chemical composition of daidzein is analogous to mammalian estrogens, and it could be useful with a dual-directional purpose by substituting/hindering with estrogen and estrogen receptor (ER) complex. Hence, daidzein puts forth shielding effects against a great number of diseases, especially those associated with the control of estr...