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Cytotoxic, antitumor and toxicological profile of Passiflora alata leaf extract

Amaral, Ricardo G.; Gomes, Silvana V. F.; Andrade, Luciana N.; dos Santos, Sara A.; Severino, Patrícia; de Albuquerque Júnior, Ricardo L. C.

Passiflora alata or passion fruit is a native flowering plant from Amazon, geographically spread from Peru to Brazil. The plant has long been used in folks medicine for its pharmacological properties and is included in the Brazilian Pharmacopoeia since 1929. The aim of this study was to evaluate the potential cytotoxic and antitumor activities of Passiflora alata leaf extract (PaLE) in S180-tumor bearing mice. ...


Abiotic factors influencing podophyllotoxin and yatein overproduction in Leptoh...

Meira, Paloma R.; David, Juceni P.; Ribeiro, Erika M. de O.; Santana, José R.F.; Brandão, Hugo N.; Oliveira, Lenaldo M. de; David, Jorge M.

Submitted by Renorbio (renorbioba@ufba.br) on 2018-04-26T18:05:48Z No. of bitstreams: 1 Abiotic factors influencing podophyllotoxin and yatein overproduction in.pdf: 597838 bytes, checksum: fb8a604acb73230b893d24a0d35dd3bc (MD5); Approved for entry into archive by Edvaldo Souza (edvaldosouza@ufba.br) on 2018-05-15T19:28:40Z (GMT) No. of bitstreams: 1 Abiotic factors influencing podophyllotoxin and yatein overpr...

Date: 2018   |   Origin: Oasisbr

Synthesis and evaluation of cytotoxic effects of Amino-ester derivatives of nat...

Victor, Mauricio M.; David, Jorge M.; Santos, Marcelo A. S. dos; Barreiros, André L. B. S.; Barreiros, Marizeth L.; Andrade, Fernanda S.

Natural α , β -amyrins were isolated from endemic Brazilian Esenbeckia grandiflora Mart., and eight synthetic derivatives were obtained by esterification reactions with bromo acetate, followed by amine treatment. The structures of the all compounds were confirmed by 1 H and 13 C nuclear magnetic resonance (NMR), Fourier transform infrared (FTIR) and high-resolution mass spectrometry (HRMS) data analysis. The de...

Date: 2017   |   Origin: Oasisbr

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