4 documents found, page 1 of 1
Genetic variants in the IFNGR2 locus associated with severe chronic Q fever
David, Suzana; Castro, Liliana; Duarte, Elsa Leclerc; Gaspar, Ulisses; da Costa Rodrigues, Maria Rosário; Cueto-Rojo, Maria Vanessa; Mendonça, JoanaQ fever is a highly contagious zoonosis capable of causing large outbreaks of important health and economic consequences. Host genetic factors are believed to influence the development of severe chronic Q fever following the infection by the etiological agent, Coxiella burnetii. Targetted next generation sequencing (NGS) was performed in a case-control genetic association study on 53 confirmed Q fever cases, in...
COVID-19: impact on Public Health and hypothesis-driven investigations on genet...
David, Suzana; Dorado, Guillermo; Duarte, Elsa Leclerc; David-Bosne, Stephanie; Trigueiro-Louro, João; Rebelo de Andrade, HelenaCOVID-19 is a new complex multisystem disease caused by the novel coronavirus SARS-CoV-2. In slightly over 2 years, it infected nearly 500 million and killed 6 million human beings worldwide, causing an unprecedented coronavirus pandemic. Currently, the international scientific community is engaged in elucidating the molecular mechanisms of the pathophysiology of SARS-CoV-2 infection as a basis of scientific de...
Characterization of the genetic diversity of Mycobacterium tuberculosis in São ...
Mendes, Natália H. [UNESP]; Melo, Fernando Af.; Santos, Adolfo Cb. [UNESP]; Pandolfi, José Rc. [UNESP]; Almeida, Elisabete A.; Cardoso, Rosilene F.Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:25:57Z No. of bitstreams: 0Bitstream added on 2014-05-27T14:47:17Z : No. of bitstreams: 1 2-s2.0-79960881158.pdf: 269242 bytes, checksum: dac50b17746f5739edcbadf223e062e4 (MD5); Made available in DSpace on 2014-05-27T11:25:57Z (GMT). No. of bitstreams: 0 Previous issue date: 2011-08-02; Background: Tuberculosis is a major...
Characterization of the genetic diversity of Mycobacterium tuberculosis in São ...
Mendes, Natália H; Melo, Fernando A.F.; Santos, Adolfo C.B.; Pandolfi, José R.C.; Almeida, Elisabete A.; Cardoso, Rosilene F.; Berghs, HenriBackground: Tuberculosis is a major health problem in São Paulo, Brazil, which is the most populous and one of the most cosmopolitan cities in South America. To characterize the genetic diversity of Mycobacterium tuberculosis in the population of this city, the genotyping techniques of spoligotyping and MIRU were applied to 93 isolates collected in two consecutive years from 93 different tuberculosis patients r...