37 documents found, page 1 of 4
METHODS FOR EXTRACTION AND ISOLATION OF AGATHISFLAVONE FROM POINCIANELLA PYRAMI...
Nascimento,Bruna O. do; David,Jorge M.Agathisflavone is a natural biflavone with restricted occurrence in plants. This biflavone presents several biological activities and can be important to developing new drugs. Obtaining such a molecule on a large scale for in vivo tests is a challenge. To date, there are no reports regarding its synthesis; thus, it is important to improve and develop methods for the purification of this bioactive compound from ...
Bergenin of Peltophorum dubium (Fabaceae) Roots and Its Bioactive Semi-Syntheti...
Silva Neto,Oscar C. da; Teodoro,Marla T. F.; Nascimento,Bruna O. do; Cardoso,Klauber V.; Silva,Eliane O.; David,Jorge M.; David,Juceni P.This work describes the isolation of pure bergenin from Peltophorum dubium roots with good yields and its further derivatization through Williamson synthesis. The alkyl derivatives of the bergenin were identified by nuclear magnetic resonance and mass spectrometry data analysis. Among them, three derivatives were reported for the first time herein, 8,10-dihexyl-bergenin, 8,10-didecyl-bergenin, and 8,10-ditetrad...
CHEMICAL COMPOSITION OF BIOLOGICAL ACTIVE EXTRACTS OF Tapirira guianensis (ANAC...
Silva,Eliezer P. da; David,Jorge M.; David,Juceni P.; Garcia,Geisse H. Trindade; Silva,Maisa T.This work describes the chemical composition of MeOH seeds and flowers extracts of Tapirira guianensis, a known tree that occurs in the Brazilian Atlantic forest. The CH2Cl2 soluble fraction of seeds extract was submitted to chromatographic procedures to obtain a mixture of new alkenyl dihydrobenzofuranoids which were identified as 2-[(10’Z)-dodec-10’-enyl]-dihydro-1-benzofuran-5-ol, 2-[(10’Z)-tridec-10’-enyl]-...
UTILIZAÇÃO DE BIOMASSA EM AULAS DE GRADUAÇÃO DE QUÍMICA ORGÂNICA EXPERIMENTAL: ...
Victor,Mauricio M.; Leite,Juliana L.; Ramos,Gabriel S.; David,Jorge M.; Cardoso,Klauber V.This work describes the importance of using renewable sources in experimental classes for undergraduate students, as well as to spread the ideas of using biomass wastes as a source of products of interest. Therefore, in the proposed experiment, citrus fruit peel waste was employed to obtain pure flavonoids by extraction and recristalization. These procedures are important to reveal to students how bioactive pro...
NEW ALKYL PHENOLS AND FATTY ACID PROFILE FROM OILS OF PULPED Spondias mombin L....
Rezende,Larissa C. de; Santos,Patricia de A.; Riatto,Valéria B.; David,Jorge M.; David,Juceni P.Spondias mombin L. is a Brazilian tree belonging to the family Anacardiaceae and popularly known as “cajá”, the genus is well known by the various exotic fruit species such as “siriguela” (S. purpurea), “umbu” (S. tuberosa) and “umbu-cajá” (S. bahiensis). It presents commercial importance to the locals especially due the small juice fruit industries and the seeds are often discarded as waste after pulping. Desp...
Influence of growth regulators on distribution of trichomes and the production ...
Passinho-Soares,Helna C.; David,Juceni P.; Santana,José R.F. de; David,Jorge M.; Rodrigues,Frederico de M.; Mesquita,Paulo R.R.; Oliveira,Fábio S. deABSTRACT The profile of volatile organic compounds, the glandular and non-glandular trichomes of Plectranthus ornatus, obtained by in vitro cultivation, was evaluated in plants grown in Murashide and Skoog medium supplemented with benylaminopurine at 4.5, 9.0, and 18.0 µM + naphthaleneacetic acid at 5.37 µM, kinetin at 4.7, 9.3 and 18.5 µM + naphthaleneacetic acid (5.37 µM) or Murashide and Skoog 0 medium (as a...
Rosmarinic and Cinnamic Acid Derivatives of in vitro Tissue Culture of Plectran...
Medrado,Héctor H.; Santos,Edlene O. dos; Ribeiro,Erika M. O.; David,Jorge M.; David,Juceni P.; Araújo,José Fernando; Vale,Ademir E. doThis work describes the tissue culture of Plectranthus ornatus Codd. (Lamiaceae) on Murashige and Skoog (MS) medium with naphthalene acetic acid (NAA) (1.0, 2.0 and 4.0 mg L-1) and 6-benzylaminopurine (BAP) (1.0, 2.0 and 4.0 mg L-1) as growth regulators to obtain the overproduction of rosmarinic acid. The content of rosmarinic acid and its biosynthetic precursors were determined by high performance liquid chrom...
Synthesis and Evaluation of Cytotoxic Effects of Amino-ester Derivatives of Nat...
Victor,Mauricio M.; David,Jorge M.; Santos,Marcelo A. S. dos; Barreiros,André L. B. S.; Barreiros,Marizeth L.; Andrade,Fernanda S.; Carvalho,Adriana A.Natural α,β-amyrins were isolated from endemic Brazilian Esenbeckia grandiflora Mart., and eight synthetic derivatives were obtained by esterification reactions with bromo acetate, followed by amine treatment. The structures of the all compounds were confirmed by 1H and 13C nuclear magnetic resonance (NMR), Fourier transform infrared (FTIR) and high-resolution mass spectrometry (HRMS) data analysis. The derivat...
COMPOSIÇÃO QUÍMICA DAS CASCAS DAS RAÍZES E FLORES DEPoincianella pyramidalis (F...
Oliveira,José Cândido S. de; David,Jorge M.; David,Juceni P.Chemical investigation of the MeOH extract of root barks of P. pyramidallis (Tul.) L. P. Queiroz resulted in the isolation of 3,3'-dimethylellagic acid and 3,3'-dimethylellagic acid-4'-O-β-D-xyloside. Lupeol, β-sitosterol/stigmasterol and the mixture of fatty acid methyl ester derivatives were also obtained. Chromatographic procedures of the MeOH extract of the flowers of this species led to obtain an unusual m...
Determination of Phenolic Acids and Quercetin in Brazilian Red Wines from Vale ...
Dias,Fabio de S.; David,Jorge M.; David,Juceni P.This work describes a method for the determination of gallic, caffeic and p-coumaric acids, as well as quercetin, in Brazilian red wines by employing reverse phase high performance liquid chromatography (RP HPLC) coupled to diode array and mass detectors. The method was performed using a sample volume of 10 µL. The limits of detections were 0.36, 0.27, 0.33 and 0.59 mg L-1 for gallic acid, caffeic acid, p-couma...