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An injectable, naproxen-conjugated, supramolecular hydrogel with ultra-low crit...

Oliveira, Carlos Bruno Pereira; Veloso, Sérgio Rafael Silva; Castanheira, Elisabete M. S.; Figueiredo, Pedro R.; Carvalho, Alexandra T.P.; Hilliou, L.

Short peptides capped on the N-terminus with aromatic groups are often able to form supramolecular hydrogels—self-assembled networks of fibrils able to trap water molecules. Typically, these hydrogelators can form stiff gels at concentrations of 0.1 to 1.0 wt%—i.e. they consist of mainly water. The properties of these soft materials mimic those of the extracellular matrix (ECM) of biological tissue and therefor...


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