Triple-negative breast cancer (TNBC) represents an aggressive subtype of breast cancer (BC) with a typically poorer prognosis than other subtypes of BC and limited therapeutic options. Therefore, new drugs would be particularly welcome to help treat TNBC. Preussin, isolated from the marine sponge-associated fungus, Aspergillus candidus, has shown the potential to reduce cell viability and proliferation as well ...
Anal cancer is rare but its incidence has been increasing particularly in the HIV-positive population in which HPV infection has increased persistence. Infection with high-risk HPV types is associated with the presence and progression of dysplastic lesions into anal cancer. For this reason, HIV positive population are considered a risk group, which should be referred for screening of anal lesions. In this artic...
O cancro anal é raro mas a sua incidência tem vindo a aumentar na população, essencialmente em indivíduos HIV positivo, nos quais a infeção por HPV tem maior persistência. A infeção por HPV de alto risco está associada à presença e progressão de lesões displásicas, precursoras de cancro anal. Por esta razão, os indivíduos HIV positivos são considerados um grupo de risco, devendo ser encaminhados para realização...