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Effects and Mechanisms of Action of Preussin, a Marine Fungal Metabolite, again...

Seabra, Rosária; Malhão, Fernanda; Correia, Alexandra; Costa, Carla; Kijjoa, Anake; Rocha, Eduardo

Triple-negative breast cancer (TNBC) represents an aggressive subtype of breast cancer (BC) with a typically poorer prognosis than other subtypes of BC and limited therapeutic options. Therefore, new drugs would be particularly welcome to help treat TNBC. Preussin, isolated from the marine sponge-associated fungus, Aspergillus candidus, has shown the potential to reduce cell viability and proliferation as well ...


Cyto-histological discrepancy: a case report of anal cytology

Silva, Andreia; Teixeira, Catarina; Seabra, Rosária; Freitas, Cristina; Ribeiro, Maria

Anal cancer is rare but its incidence has been increasing particularly in the HIV-positive population in which HPV infection has increased persistence. Infection with high-risk HPV types is associated with the presence and progression of dysplastic lesions into anal cancer. For this reason, HIV positive population are considered a risk group, which should be referred for screening of anal lesions. In this artic...

Date: 2017   |   Origin: Citotech Online - Case Review

Discrepância cito-histológica: estudo de caso em citologia do canal anal

Silva, Andreia; Teixeira, Catarina; Seabra, Rosária; Freitas, Cristina; Ribeiro, Maria

O cancro anal é raro mas a sua incidência tem vindo a aumentar na população, essencialmente em indivíduos HIV positivo, nos quais a infeção por HPV tem maior persistência. A infeção por HPV de alto risco está associada à presença e progressão de lesões displásicas, precursoras de cancro anal. Por esta razão, os indivíduos HIV positivos são considerados um grupo de risco, devendo ser encaminhados para realização...


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