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Ghrelin expression in human and rat fetal lungs and the effect of ghrelin admin...

Santos, Marta; Bastos, Pedro; Gonzaga, Silvia; Roriz, José-Mário; Baptista, Maria J.; Silva, Cristina Isabel Nogueira; Rocha, Gustavo Filipe Melo Alves

Ghrelin is a strong physiologic growth hormone secretagogue that exhibits endocrine and non-endocrine actions. In this study, ghrelin expression in humans and rats was evaluated throughout development of normal and hypoplastic lungs associated with congenital diaphragmatic hernia (CDH). Additionally, the effect of antenatal treatment with ghrelin in the nitrofen-induced CDH rat model was tested. In normal lungs...

Date: 2006   |   Origin: RepositóriUM - Universidade do Minho
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