3 documents found, page 1 of 1
Randomized, double-blind, phase III clinical study of a novel nanotechnological...
Gobbato, Cintia Aparecida Rodrigues Santiago, 1970-; Gobbato, André Alves de Moraes, 1964-; Magalhães, Tainah Babadopulos; Moreno, Ronilson AgnaldoAgradecimentos: This study was funded by Biolab Indústria Farmacêutica Ltd., Brazil and Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP - Grant n° 2016/22506-1); Abstract: Nanotechnology may increase the speed of penetration into the skin. This study evaluated the efficacy, safety, and pharmacokinetics of a novel topical anesthetic nanocapsule formulation (2 g) containing 2.5% lidocaine and 2.5% pr...
Impact of bariatric surgery on the pharmacokinetics parameters of amoxicillin
De Nucci, Gilberto, 1958-; Antunes, Natalícia de JesusAgradecimentos: This work was supported by the Brazilian Ministry of Science and Technology and the National Council for Scientific and Technological Development through the public announcement PQ10/2011 - productivity in research - PQ-2011 (grant number 309228/2011-5); Abstract: Bariatric surgery leads to several anatomo-physiological modifications that may affect pharmacokinetic parameters and consequently al...
Quantification of estradiol cypionate in plasma by liquid chromatography couple...
Martins, Roberto Salvador, 1970-; Antunes, Natalícia de Jesus; Moreno, Ronilson Agnaldo; De Nucci, Gilberto, 1958-Agradecimentos: This study was funded by Biolab Sanus Farmacêutica Ltda., Brazil; Abstract: The combination of medroxyprogesterone acetate 25 mg + estradiol cypionate 5 mg is a highly effective, monthly injectable contraceptive. For the first time, this study presents the development and validation of a sensitive method for estradiol cypionate analysis in human plasma by liquid chromatography coupled with tande...