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Establishment, molecular and biological characterization of HCB-514: a novel hu...
Rosa, Marcela Nunes; Evangelista, Adriane Feijó; Leal, Letícia Ferro; De Oliveira, Cristina Mendes; Silva, Viviane Aline OliveiraCervical cancer is the fourth most common cancer in women. Although cure rates are high for early stage disease, clinical outcomes for advanced, metastatic, or recurrent disease remain poor. To change this panorama, a deeper understanding of cervical cancer biology and novel study models are needed. Immortalized human cancer cell lines such as HeLa constitute crucial scientific tools, but there are few other ce...
Loss of Raf kinase inhibitor protein expression is associated with human papill...
Bidinotto, Lucas Tadeu; Véo, Carlos A. R.; Loaiza, Edgar Aleman; Ribeiro, Guilherme G.; Lorenzi, Adriana T.; Rosa, Luciana Albina ReisThere has been an increase in the incidence of anal cancer in the past two decades, with squamous cell carcinoma (SCC) being the most frequent histological type identified. Among the risk factors, high-risk human papillomavirus (HPV) infection is the most pervasive. Raf kinase inhibitor protein (RKIP) is expressed in a number of normal human tissues and previous studies have demonstrated the prognostic value of...