9 documents found, page 1 of 1
Treatment package time in high-risk oral cavity squamous cell carcinoma
Ferreira, Pedro; Esteves, Susana; Vilares, Miguel; Montalvão, Pedro; Rito, Miguel; Magno, Sara; Sargento, Isabel; Colaço, Raul; Netto, EduardoBackground: The gold-standard of treatment for oral cavity squamous cell carcinoma (OCSCC) is surgery and adjuvant chemoradiotherapy (CRT) in the sub-group of high-risk patients. In this group of patients, treatment time is an important factor in clinical outcomes. We aim to study the influence of the treatment package time (TPT). Materials and methods: We conducted a retrospective study of patients with high-r...
Epidemiology and risk factors for Schistosoma spp. infection in adult populatio...
Serra, João Tiago; Silva, Carina; Sidat, Mohsin; Belo, Silvana; Ferreira, Pedro; Ferracini, Natália; Kaminstein, Daniel; Conceição, CSchistosomiasis is a neglected tropical disease that remains an important public health problem. Mozambique is one of the countries with the highest prevalence of the disease. Adults with chronic schistosomiasis can act as a reservoir for continued infection transmission. Data about schistosomiasis in this population in Mozambique is limited. In order to determine schistosomiases prevalence and risk factors in ...
Morbidity associated with schistosomiasis in adult population of Chókwè distric...
Serra, João Tiago; Silva , Carina; Sidat, Mohsin; Belo, Silvana; Ferreira, Pedro; Ferracini, Natália; Kaminstein, Daniel; Thompson, RicardoPublisher Copyright: © 2024 Serra et al. Funding: This work was funded by the "Joint WHO-AFRO/TDR/EDCTP Small Grants Scheme for implementation research on infectious diseases of poverty 2017”, whose responsible investigator was RT. Additionally, it received financial support from “Associação para Desenvolvimento da Medicina Tropical”, whose responsible investigator was JTS and from Fundação para a Ciência e a T...
Brain-first forms of Parkinson's disease are over-represented in patients with ...
Mendonça, Marcelo D.; Ferreira, Pedro; Barbosa, Raquel; da Silva, Joaquim AlvesPublisher Copyright: © 2024 The Authors; Motor subtypes in Parkinson's Disease (PD) are unstable over time, limiting mechanistic insights and biomarker discovery. We focused on Rest Tremor (RT) as a symptom to test for phenotype stability and link it to specific circuits and disease mechanisms. Using the PPMI cohort data over 5 years we found that RT is more stable than classical Tremor-Dominant definitions, a ...
Vernonia britteniana Root Phytochemical Studies, In Vitro Cercaricidal Activity...
Valente, Maria dos Anjos; Ferreira, Pedro; Lima, Katelene; Moreira da Silva, Isabel B.; Nobre, Paula; Neto, Isabel; Pires, Mavilde; Braz, Berta SãoFunding Information: This research was funded by the Foundation for Science and Technology (FCT, Portugal) through national funds FCT/MCTES to iMed.ULisboa (UIDP/04138/2020). Publisher Copyright: © 2023 by the authors.; Vernonia britteniana Hiern. (Asteraceae) is a medicinal plant used in traditional Angolan medicine against schistosomiasis. Our study aimed to investigate the phytochemical composition and the c...
A prospective observational study for a Federated Artificial Intelligence solut...
Lemos, Raquel; Areias-Marques, Sofia; Ferreira, Pedro; O’Brien, Philip; Beltrán-Jaunsarás, María Eugenia; Ribeiro, Gabriela; Martín, MiguelFunding Information: AJO-M was national coordinator for Portugal of a non-interventional study (EDMS-ERI-143085581, 4.0) to characterize a Treatment-Resistant Depression Cohort in Europe, sponsored by Janssen-Cilag, Ltd (2019–2020), is recipient of a grant from Schuhfried GmBH for norming and validation of cognitive tests, and is national coordinator for Portugal of trials of psilocybin therapy for treatment-re...
A Comparative Proteomic Analysis of Praziquantel-Susceptible and Praziquantel-R...
Pinto-Almeida, António; Mendes, Tiago M.F.; Ferreira, Pedro; Abecasis, Ana B.; Belo, Silvana; Anibal, Fernanda F.; Allegretti, Silmara M.Funding Information: We acknowledge the Mass Spectrometry Laboratory at Brazilian Biosciences National Laboratory, CNPEM, Campinas, Brazil for their support with the mass spectrometry analysis. The authors would like to thank Professor Ana Tomás from IBMC and GABBA program (Porto, Portugal), for very helpful suggestions that improved greatly this paper. Funding Information: This work was initially supported by ...
Application of artificial intelligence algorithms to estimate the success rate ...
Guimarães, Beatriz Cartaxo Brás de Vasconcellos; Martins, Leonardo; Metello, José Luís; Luís-Ferreira, Fernando; Ferreira, Pedro; Fonseca, José ManuelThis work is funded in part by the Portuguese “Fundação para a Ciência e a Tecnologia” (FCT) in the context of the Centre of Technology and Systems CTS/UNINOVA/FCT/NOVA, reference UIDB/00066/2020.; The aim of this study was to build an Artificial Neural Network (ANN) complemented by a decision tree to predict the chance of live birth after an In Vitro Fertilization (IVF)/Intracytoplasmic Sperm Injection (ICSI) ...
New insights about the monomer and homodimer structures of the human AOX1
Ferreira, Pedro; Cerqueira, N. M. F. S. A.; Coelho, C.; Fernandes, P. A.; Romão, M. J.; Ramos, M. J.UID/MULTI/04378/2019. IF/01310/2013 . PhD Grant SFRH/BD/119206/2016.; Human aldehyde oxidase (hAOX1) is a molybdenum dependent enzyme that plays an important role in the metabolism of various compounds either endogenous or xenobiotics. Due to its promiscuity, hAOX1 plays a major role in the pharmacokinetics of many drugs and therefore has gathered a lot of attention from the scientific community and, particular...