3 documents found, page 1 of 1
Personalized bacteriophage therapy outcomes for 100 consecutive cases: a multic...
Pirnay, Jean-Paul; Djebara, Sarah; Steurs, Griet; Griselain, Johann; Cochez, Christel; De Soir, Steven; Glonti, Tea; Spiessens, An; Vanden Berghe, EmilyIn contrast to the many reports of successful real-world cases of personalized bacteriophage therapy (BT), randomized controlled trials of non-personalized bacteriophage products have not produced the expected results. Here we present the outcomes of a retrospective observational analysis of the first 100 consecutive cases of personalized BT of difficult-to-treat infections facilitated by a Belgian consortium i...
Pseudomonads from wild free-living sea turtles in Principe Island, Gulf of Guinea
Oliveira, Manuela; Serrano, Isa; Santos, Jose Pedro; Bilocq, Florence; Pereira, Nuno; Loureiro, Nuno de Santos; Tavares, Luis; Pirnay, Jean-PaulDissemination of antibiotic resistance is a major concern, especially in aquatic environments, where pollution contributes for resistant bacteria selection. These strains may have serious health implications, especially for endangered species, including the sea turtles' hawksbill Eretmochelys imbricata and green turtles Chelonia mydas. We aimed to evaluate the presence of antibiotic resistant pseudomonads in wi...
The phage therapy paradigm: prêt-à-porter or sur-mesure?
Pirnay, Jean-Paul; De Vos, Daniel; Verbeken, Gilbert; Merabishvili, Maia; Chanishvili, Nina; Vaneechoutte, Mario; Zizi, Martin; Laire, GeertThe present opinion is the result of discussions on the future of phage therapy (personalized or large-scale uniform therapy?) during the first International Congress on Viruses of Microbes, held at the Institut Pasteur in Paris on June 21–25, 2010.