5 documents found, page 1 of 1

Exposição repetida à cafeína aumenta a atividade locomotora induzida pelo fempr...

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Ontogênese, estresse e dependência de substâncias psicoativas

Submitted by Guilherme Lemeszenski (guilherme@nead.unesp.br) on 2013-08-22T18:41:06Z No. of bitstreams: 1 S1516-93322007000300003.pdf: 165747 bytes, checksum: c6d842523711af4bc0404044c95a7526 (MD5); Made available in DSpace on 2013-08-22T18:41:06Z (GMT). No. of bitstreams: 1 S1516-93322007000300003.pdf: 165747 bytes, checksum: c6d842523711af4bc0404044c95a7526 (MD5) Previous issue date: 2007-09-01; Made availabl...

Substâncias psicoativas: dependência & estresse

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This article comments on some aspects of participation of dopaminergic mesocorticolimbic system in the rewarding properties of psychostimulant drugs. It also emphasizes the involvement of dopamine D1 and D2 receptors in the reinforcing effect, and their interactions with several types of receptors, which include opioid receptors and glutamate receptors. The level of activation of these systems may be related to...

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Fencamfamine (FCF) is a psychostimulant classified as an indirect dopamine agonist and abuse of this drug has been reported. The conditioning place preference (CPP) paradigm was used to investigate the reinforcing properties of FCF. Some metodological aspects of the CPP induced by FCF such as extinction of confitioning and lack of plasma FCF concentration during test-sessions are presently commented.; A fencanf...