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The Acute Effects of a Fast-Food Meal Versus a Mediterranean Food Meal on the A...

Silva, D.; Mendes, F.C.; Stanzani, V.; Moreira, R.; Pinto, M.; Beltrao, M.; Sokhatska, O.; Severo, M.; Padrão, Patrícia; Garcia-Larsen, V.; Delgado, L.

Background/Objectives: This study aimed to assess the acute effects of two isoenergetic but micronutrient-diverse meals-a Mediterranean-like meal (MdM) and a fast food-like meal (FFM)-on the autonomic nervous system (ANS), lung function, and airway inflammation response. Methods: Forty-six participants were enrolled in a randomized crossover clinical trial, consuming two isoenergetic meals: FFM (burger, fries, ...


Airborne food allergen and aeroallergen levels in healthcare settings: an unacc...

Leal, M.; Paciência, I.; Farraia, M.; Cavaleiro Rufo, J.; Castro Mendes, F.; Delgado, L.; Viegas, Carla; Moreira, A.

Background: Exposure to airborne allergens of biological origin associates with the development and exacerbation of allergic asthma and rhinitis. Assessment of allergens' exposure in healthcare facilities may contribute to monitor hygiene and survey specific allergens which may cause symptoms in sensitized subjects. Objective: To assess the concentration of indoor and airborne food allergens across different he...


Hypersensitivity pneumonitis: antigen diversity and disease implications

Nogueira, R.; Melo, N.; Bastos, Hélder Novais; Martins, N.; Delgado, L.; Morais, A.; Mota, P. C.

Hypersensitivity pneumonitis (HP) is an immune-mediated syndrome triggered by inhalation of a wide variety of allergens, to which an individual has previously been sensitized. More than 200 agents responsible for the disease have already been identified; however, HP occurs only in a small number of individuals exposed to causal antigens. The present report provides an overview of the role of antigen role in HP,...


Swimming pool training environment may drive skin and gut dysbiosis in elite sw...

Ribeiro Paciência, I.; Pereira, P.; Aho, V.; Cavaleiro Rufo,J.; Silva, D.; Martins, C.; Mendes, F.; Rama, T.; Rodolfo, A.; Leão, L.; Delgado, L.


Associations between sarcoidosis clinical course and ANXA11 rs1049550 C/T, BTNL...

Morais, A.; Lima, B.; Alves, H.; Melo, N.; Mota, P.C.; Marques, A.; Delgado, L.

Background: A genetic background may be responsible for the different clinical courses in sarcoidosis. We analyzed associations between sarcoidosis clinical course and HLA class I/II alleles and susceptibility gene SNPs ANXA11 rs1049550 C/T and BTNL2 rs2076530 G/A in a Portuguese population, investigating possible gene–gene interactions. Methods: We studied 138 unrelated Caucasian sarcoidosis patients (78 women...


Science with e-ASTROGAM (a space mission for MeV-GeV gamma-ray astrophysics)

De Angelis, A.; Tatischeff, V.; Grenier, I. A.; McEnery, J.; Mallamaci, M.; Tavani, M.; Oberlack, U.; Hanlon, L.; Walter, R.; Argan, A.

e-ASTROGAM (enhanced ASTROGAM) is a breakthrough Observatory space mission, with a detector composed by a Silicon tracker, a calorimeter, and an anticoincidence system, dedicated to the study of the non-thermal Universe in the photon energy range from 0.3 MeV to 3 GeV - the lower energy limit can be pushed to energies as low as 150 keV for the tracker, and to 30 keV for calorimetric detection. The mission is ba...


"Milk, dairy products and fruit" dietary pattern is associated with reduced ast...

Barros, Renata; Moreira, André; Padrão, Patrícia; Teixeira, Vitor Hugo; Lopes, C.; Severo, M.; Delgado, L.; Moreira, Pedro


Bacterial and fungal exposure in schools may influence asthma and allergy in ch...

Cavaleiro Rufo, João; Madureira, J.; Paciência, I.; Aguiar, L.; Delgado, L.; Teixeira, J.P.; de Oliveira Fernandes, E.; Moreira, A.

Development of allergic diseases may be regulated by microbial exposure. Children spend a lot of their time in schools, under an extensive diversity of biological agents, such as bacteria and fungi. This study aimed to characterize indoor air microbiological exposure in schools as a predictor of allergic sensitization and asthma in children.


Filaggrin polymorphism Pro478Ser is associated with the severity of atopic derm...

Lopes, C.; Rocha, L.; Sokhatska, O.; Soares, J.; Tavaria, Freni; Correia, O.; Pintado, M. E.; Fernandes, S.; Delgado, L.; Moreira, A.


Exposure to emissions from cleaning products in primary schools: a test chamber...

Cavaleiro Rufo, João; Madureira, J.; Paciência, I.; Sousa, J.; Oliveira Fernandes, E.; Slezakova, K.; Pereira, M.C.; Aguiar, L.; Teixeira, J.P.

The aim of this study was to investigate volatile organic compound (VOC) emissions from floor cleaning products (FCPs) used in primary schools and compare them with emissions from a previously recognised low-emitting product (control sample). Samples of FCPs used in 3 primary schools and a control sample were collected and subsequently examined in a test chamber. Measurements were performed at t = 0, 60, 120, 2...


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